Fatty fish intake and cognitive function: FINS-KIDS, a randomized controlled trial in preschool children

Table 4 Predicted change in 9-Hole Peg Test (9-HPT) seconds after study meals with meat (n = 113) or fish (n = 105)

	Main analyses					Sub-analyses
				Models adjusted for
				Pre-score, age^b		Pre-score, age, compliance^c		Pre-score, age, compliance, interaction treatment*compliance^d
Intervention	Pre Mean (SD)	Post Mean (SD)	p ^a	Change Mean (95% CI)	p	Change Mean (95% CI)	p	Change Mean (95% CI)	p
9-HPT
Dominant hand
Fish	30.6 (7.8)	27.9 (6.1)	< 0.0001	−2.7 (−3.6 to −1.8)	0.19	−2.8 (−3.7 to −1.9)	0.09	−2.9 (−3.8 to −1.9)
Meat	30.5 (7.6)	28.7 (6.1)	0.0043	−1.8 (−2.7 to −1.0)		− 1.7 (−2.6 to −0.8)		− 1.8 (−2.7 to −0.8)
Model fit^e							0.19		0.65
Non-dominant hand
Fish	37.0 (10.3)	32.7 (7.6)	< 0.0001	−4.2 (−5.3 to −3.2)	0.0470	−4.5 (−5.6 to −3.4)	0.0110	−4.8 (−5.9 to −3.6)
Meat	36.6 (8.9)	34.0 (7.4)	0.0003	−2.7 (−3.8 to −1.7)		− 2.5 (−3.5 to −1.4)		−2.8 (−3.9 to −1.7)
Model fit^e							0.0046		0.0027

Pre- and post-intervention data are given as mean (SD), change as mean (95% CI)
Abbreviations: CI confidence interval, SD standard deviation
^aPaired samples t test for comparison of individual pre- and post-intervention values within each intervention group
^bLinear mixed effect model adjusted for pre-intervention score and age
^cLinear mixed effect model adjusted for pre-intervention score, age, and compliance (amount of fish/meat consumed)
^dLinear mixed effect model adjusted for pre-intervention score, age, and interaction between treatment (intervention group) and compliance, mean values
^eLikelihood ratio test to compare the goodness of fit to the previous model
A random intercept for kindergarten was included in all linear mixed model analyses

ISSN: 1741-7015