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Table 2 Clinical trial registration and results reporting policies

From: Clinical trial registration and reporting: a survey of academic organizations in the United States

QUESTION (number of participants who viewed the question) No. Percentage
Trial registration policies   
 Does the organization have a registration policy? (N = 366)a   
  Yes 156 43%
  No 173 47%
  Don’t know 37 10%
 Does the policy cover investigators joining the organization? (N = 156)b   
  Yes 57 37%
  No 76 49%
  Don’t know 23 15%
  Skipped (did not answer) 0 0%
 Does the policy cover investigators leaving the organization? (N = 156)b   
  Yes 38 24%
  No 87 56%
  Don’t know 31 20%
  Skipped (did not answer) 0 0%
 According to the policy, when must trials be registered? (N = 139)b,c   
  Before IRB approval 15 11%
Before enrollment begins 49 35%
  Within 21 days of beginning enrollment 31 22%
  Requirements differ among trials 21 15%
  This is not addressed in the policy 18 13%
  Don’t know 4 3%
  Skipped (did not answer) 1 1%
 According to the policy, who is responsible for determining whether a trial must be registered? (N = 129)b,c
  Principal investigator 72 56%
  Institutional review board 20 16%
  PRS administrator 35 27%
  Other 14 11%
  This responsibility is not assigned in the policy 12 9%
  Don’t know 0 0%
  Skipped (did not answer) 0 0%
 According to the policy, can investigators be penalized by the organization for failing to register a trial? (N = 139)b
  Yes 27 23%
  No 91 91%
  Don’t know 21 21%
  Skipped (did not answer) 0 0%
 Date the trial registration policy came into effect (N = 139)b,d
  Minimum (year) 2000  
  Maximum (year) 2016  
  Median (year) 2013  
Results reporting policies
 Does the organization have a results reporting policy? (N = 366)a
  Yes 129 35%
  No 193 53%
  Don’t know 44 12%
 According to the policy, who is responsible for monitoring if results are reported on time? (N = 115)b,c
  Principal investigator 54 47%
  Institutional review board 5 4%
  PRS administrator 68 59%
  Other 12 10%
  This responsibility is not assigned in the policy 18 16%
  Don’t know 1 1%
  Skipped (did not answer) 0 0%
 According to the policy, can investigators be penalized by the organization for failing to report a trial (N = 114)e
  Yes 21 18%
  No 75 66%
  Don’t know 18 16%
  Skipped (did not answer) 0 0%
  1. aAn answer to this question was required for an account to be included in the analysis; accounts that did not see or skipped this question were excluded from all analyses
  2. bThe number of possible responses (i.e., the denominator) includes the accounts with a relevant policy that viewed this question. The number of accounts that viewed each question is less than the total number of accounts in the study because (1) participants did not see all questions because of skip logic, and (2) some participants discontinued the survey before viewing all questions
  3. cBecause participants could “check all that apply,” the sum of all categories exceeds the number of participants who responded (i.e., some participants selected multiple responses)
  4. dBecause 50 (36%) selected “Don’t know,” 89 accounts are included in the analysis
  5. eOf 111 accounts who viewed either question about penalties for (1) failing to register or (2) failing to report a trial, 17 (15%) responded “Yes” to both questions, and 31 (28%) responded “Yes” to one or both questions