Table 1 Characteristics of population by CTF cases and control status
Characteristic | All n = 290 | CTF n = 124 (43%) | Controls n = 166 (57%) | p valuea |
|---|---|---|---|---|
Gender | ||||
 Male | 160 (55) | 71 (44) | 89 (56) | 0.55 |
 Female | 130 (45) | 53 (41) | 77 (59) |  |
Age (years) | 35.0 (29.0–42.0) | 35.5 (29.5–42.0) | 35.0 (29.0–42.0) | 0.81 |
Country | ||||
 Brazil | 44 (15) | 16 (36) | 28 (64) | 0.001 |
 Haiti | 34 (12) | 11 (32) | 23 (68) |  |
 India | 23 (8) | 18 (78) | 5 (22) |  |
 Malawi | 38 (13) | 22 (58) | 16 (42) |  |
 Peru | 19 (7) | 4 (21) | 15 (79) |  |
 South Africa | 38 (13) | 20 (53) | 18 (47) |  |
 Thailand | 23 (8) | 6 (26) | 17 (74) |  |
 USA | 44 (15) | 17 (39) | 27 (61) |  |
 Zimbabwe | 27 (9) | 10 (37) | 17 (63) |  |
Body mass index (kg/m2) | ||||
 < 18.5 | 29 (10) | 18 (62) | 11 (38) | 0.001 |
 18–25 | 192 (66) | 89 (46) | 103 (54) |  |
 ≥ 25 | 69 (24) | 17 (25) | 52 (75) |  |
Prior TB diagnosis | ||||
 Yes | 59 (20) | 34 (58) | 25 (42) | 0.01 |
 No | 231 (80) | 90 (39) | 141 (61) |  |
Treatment arm | ||||
 A | 100 (35) | 58 (56) | 45 (44) | 0.72 |
 B | 108 (37) | 54 (42) | 39 (58) | |
 C | 82 (28) | 67 (29) | 27 (71) | |
CD4 count (cells/mm3) | ||||
 < 100 | 103 (36) | 50 (69) | 22 (31) | < 0.001 |
 100–200 | 93 (32) | 45 (49) | 46 (51) |  |
 > 200 | 94 (34) | 43 (41) | 63 (59) |  |
Log viral load (copies/mL) | ||||
 < 4 | 21 (7) | 6 (29) | 15 (71) | 0.18 |
 4–5 | 98 (34) | 38 (39) | 60 (61) |  |
 > 5 | 171 (59) | 80 (47) | 91 (53) |  |
Hypoalbuminemia | ||||
 Yes (≤ 3.5 g/dL) | 77 (19) | 51 (41) | 26 (16) | < 0.001 |
 No (> 3.5 g/dL) | 215 (81) | 73 (59) | 140 (84) |  |
Anemia | ||||
 Yes | 168 (58) | 87 (54) | 81 (46) | < 0.001 |
 No | 121 (42) | 36 (50) | 85 (50) |  |