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Table 9 Association between abnormal blood tests and frailty

From: Frailty, nutrition-related parameters, and mortality across the adult age spectrum

Blood tests Linear regression analysis
β-coefficient (95%CI) p value
Total lymphocyte count Low 0.010 (0.005, 0.015) < 0.001*
Haemoglobin Low 0.048 (0.042, 0.055) < 0.001*
High − 0.003 (− 0.022, 0.017) 0.798
Mean corpuscular volume Low 0.037 (0.027, 0.046) < 0.001*
High 0.041 (0.029, 0.053) < 0.001*
Albumin Low 0.037 (0.029, 0.046) < 0.001*
Vitamin A Low 0.085 (0.030, 0.139) 0.002*
High 0.051 (0.044, 0.059) < 0.001*
Vitamin C Low 0.011 (0.003, 0.019) 0.005*
High − 0.001 (− 0.013, 0.011) 0.845
Vitamin D Low 0.015 (0.011, 0.019) < 0.001*
High − 0.150 (− 0.036, 0.006) 0.160
Pyridoxine Low 0.015 (0.010, 0.020) < 0.001*
Folate, RBC Low − 0.008 (− 0.017, 0.001) 0.093
Cobalamin Low 0.006 (− 0.005, 0.018) 0.287
α-carotene Low 0.023 (0.018, 0.028) < 0.001*
High − 0.023 (− 0.030, − 0.017) < 0.001*
β-carotene Low 0.025 (0.020, 0.030) < 0.001*
High − 0.022 (− 0.028, − 0.016) < 0.001*
β-cryptoxanthin Low 0.031 (0.026, 0.036) < 0.001*
High − 0.017 (− 0.022, − 0.012) < 0.001*
Lutein/Zeaxanthin Low 0.032 (0.028, 0.036) < 0.001*
High − 0.018 (− 0.027, − 0.009) < 0.001*
Lycopene Low 0.022 (0.017, 0.027) < 0.001*
High − 0.008 (− 0.014, − 0.002) 0.014*
Iron, serum Low 0.021 (0.016, 0.027) < 0.001*
High 0.001 (− 0.015, 0.016) 0.947
Creatinine Low 0.008 (0.000, 0.016) 0.048*
High 0.070 (0.062, 0.078) < 0.001*
Total cholesterol High − 0.015 (− 0.019, − 0.011) < 0.001*
Triglyceride High 0.017 (0.013, 0.021) < 0.001*
HDL-c Low 0.012 (0.008, 0.016) < 0.001*
LDL-c High − 0.018 (− 0.024, − 0.012) < 0.001*
Glucose Low 0.014 (0.001, 0.026) 0.029*
High 0.031 (0.027, 0.036) < 0.001*
Homocysteine High 0.056 (0.039, 0.073) < 0.001*
  1. All analyses were adjusted for age, sex, race, energy intake, educational level, marital status, employment status, smoking and study cohort
  2. HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, RBC red blood cell, *p value < 0.05