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Table 6 Sensitivity analysis of complete case analysis compared to imputed ADL adjusted model with respect to primary outcome (n = 5007)

From: Living at home after emergency hospital admission: prospective cohort study in older adults with and without cognitive spectrum disorder

Variables N (%; 95%CI) with positive outcome at 30 days Adjusted model Sensitivity analysis*
Complete case analysis
Total N = 5007 Odds ratio (95% confidence interval)
Age
65–74 (n = 1777) 1683 (94.7; 93.6–95.7) 1 1
75–85 (n = 2318) 2092 (90.3; 89.0–91.4) 0.64 (0.49–0.83) 0.68 (0.51–0.92)
≥ 85 (n = 1475) 1232 (83.5; 81.6–85.3) 0.43 (0.33–0.56) 0.48 (0.35–0.65)
Sex
Women (n = 3138) 2811 (89.6; 88.5–90.6) 1 1
Men (n = 2432) 2196 (90.3; 89.0–91.4) 0.90 (0.75–1.09) 0.91 (0.74–1.13)
Deprivation (SIMD quintile)
1 most deprived (n = 1151) 1054 (91.6; 89.8–93.0) 1.11 (0.81–1.54) 1.32 (0.92–1.89)
2 (n = 1473) 1323 (89.8; 88.2–91.3) 0.92 (0.69–1.25) 0.91 (0.66–1.27)
3 (n = 1266) 1131 (89.3; 87.5–90.9) 0.92 (0.68–1.25) 1.04 (0.74–1.46)
4 (n = 853) 752 (88.2; 85.8–90.2) 0.88 (0.64–1.22) 0.93 (0.65–1.33)
5 most affluent (n = 827) 747 (90.3; 88.1–92.2) 1 1
Charlson Comorbidity Index (CCI)
CCI 0 (n = 1424) 1284 (90.2; 88.5–91.6) 1 1
CCI 1 (n = 1496) 1357 (90.7; 89.1–92.1) 0.87 (0.67–1.13) 0.92 (0.69–1.23)
CCI 2 to 5 (n = 2233) 2024 (90.6; 89.4–91.8) 0.97 (0.76–1.23) 0.96 (0.74–1.26)
CCI ≥ 6 (n = 417) 342 (82.0; 78.0–85.4) 0.34 (0.24–0.47) 0.35 (0.24–0.51)
Cognitive spectrum disorder
None (n = 3903) 3645 (93.4; 92.6–94.1) 1 1
Delirium alone (n = 821) 704 (85.7; 83.2–88.0) 0.57 (0.44–0.72) 0.53 (0.41–0.70)
Known dementia (n = 335) 270 (80.6; 76.0–84.5) 0.43 (0.31–0.59) 0.46 (0.32–0.66)
Delirium superimposed on dementia (n = 285) 197 (69.1; 63.4–74.2) 0.25 (0.18–0.34) 0.29 (0.21–0.39)
Unspecified cognitive impairment (n = 226) 191 (84.5; 79.2–88.7) 0.55 (0.37–0.82) 0.60 (0.40–0.91)
No. of medications
0–5 (n = 1746) 1571 (90.0; 88.5–91.3) 1 1
6–10 (n = 2204) 1965 (89.2; 87.8–90.4) 0.96 (0.77–1.19) 1.08 (0.85–1.37)
> 10 (n = 1620) 1471 (90.8;89.3–92.1) 1.15 (0.90–1.48) 1.42 (1.07–1.88)
Activities of daily living (ADL) score
Persistently high ADL (n = 1956) 1835 (93.8; 92.6–94.8) 1 1
Changed ADL (n = 1341) 1156 (86.2; 84.3–87.9) 0.41 (0.32–0.52) 0.35 (0.26–0.46)
Persistently low ADL (n = 681) 515 (75.6; 72.2–78.8) 0.63 (0.51–0.78) 0.55 (0.43–0.71)
  1. Italic text denotes results which are statistically significant
  2. 95%CI 95% confidence interval; SIMD Scottish Index of Multiple Deprivation
  3. *Complete case analysis based on data from n = 3978 (71.4%) who had complete data recorded