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Table 2 Discontinuation of adjuvant hormone therapy and breast cancer events in women diagnosed with breast cancer in Stockholm, Sweden, 2001–2008. (A) Screening non-participants vs participants, (B) screening non-participants vs participants diagnosed with screen-detected cancers, and (C) screening non-participants vs participants diagnosed with interval cancers

From: Discontinuation of adjuvant hormone therapy among breast cancer patients not previously attending mammography screening

 

Discontinuation of adjuvant hormone therapy, no. (%)

Multivariable-adjusted, HRa (95% CIs)

Breast cancer events, no. (%)

Multivariable-adjusted, HRa (95% CIs)

 

No

Yes

No

Yes

(A) Non-participants vs participants

 Participants

822 (50.5)

805 (49.5)

1.00 (reference)

3449 (83.0)

707 (17.0)

1.00 (reference)

 Non-participants

146 (43.1)

193 (56.9)

1.30 (1.11–1.53)

719 (76.3)

223 (23.7)

1.22 (1.05–1.42)

(B) Non-participants vs participants (screen-detected cancers)

 Participants (screen-detected cancers)

615 (50.1)

612 (49.9)

1.00 (reference)

2523 (85.5)

427 (14.5)

1.00 (reference)

 Non-participants

146 (43.1)

193 (56.9)

1.31 (1.10–1.54)

719 (76.3)

223 (23.7)

1.32 (1.12–1.57)

(C) Non-participants vs participants (interval cancers)

 Participants (interval cancers)

207 (51.8)

193 (48.2)

1.00 (reference)

926 (76.8)

280 (23.2)

1.00 (reference)

 Non-participants

146 (43.1)

193 (56.9)

1.25 (1.02–1.53)

719 (76.3)

223 (23.7)

1.05 (0.88–1.25)

  1. aHazard ratio (HR) and 95% confidence intervals (95% CIs) adjusted for age, country of birth, marital status, tumor size, lymph node involvement, estrogen receptor status, progesterone receptor status, and grade