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Table 7 Odds ratios (95% confidence intervals) of groups of mental disorders (lifetime prevalence) regressed on immune-mediated classes, men and women

From: A step beyond the hygiene hypothesis—immune-mediated classes determined in a population-based study

 

Neutral class

Resilient class

Atopic class

Mixed class

ACE class

Men

 Neurodevelopmental disorders

1 (ref.)

0.8 (0.5–1.2)

1.7 (1.0–3.0)

2.0 (1.3–3.2)

4.0 (2.4–6.5)

 Early anxiety disorders

1 (ref.)

0.8 (0.6–1.1)

1.1 (0.7–1.8)

2.0 (1.4–2.8)

2.7 (1.7–4.3)

 Late anxiety disorders

1 (ref.)

0.7 (0.5–1.0)

1.2 (0.7–2.1)

1.5 (1.0–2.4)

1.6 (0.9–2.9)

 Mood disorders

1 (ref.)

0.8 (0.7–1.0)

1.5 (1.0–2.2)

1.8 (1.3–2.5)

2.3 (1.5–3.4)

 Substance disorders

1 (ref.)

0.9 (0.7–1.2)

1.1 (0.7–1.6)

1.1 (0.8–1.6)

1.8 (1.1–2.8)

Women

 Neurodevelopmental disorders

1 (ref.)

0.6 (0.3–1.0)

0.9 (0.4–1.8)

1.6 (0.9–2.6)

3.8 (2.3–6.2)

 Early anxiety disorders

1 (ref.)

0.7 (0.5–0.9)

1.6 (1.2–2.2)

1.4 (1.1–1.9)

3.0 (2.1–4.2)

 Late anxiety disorders

1 (ref.)

0.8 (0.6–1.1)

1.2 (0.8–1.8)

1.6 (1.1–2.2)

2.7 (1.9–4.0)

 Mood disorders

1 (ref.)

0.9 (0.7–1.0)

1.1 (0.8–1.5)

1.4 (1.1–1.9)

2.2 (1.5–3.2)

 Substance disorders

1 (ref.)

0.6 (0.4–1.0)

1.8 (1.0–3.0)

1.6 (1.0–2.6)

2.7 (1.6–4.6)

  1. ACE adverse childhood experiences
  2. Groups of mental disorders: neurodevelopmental disorders—tics, attention-deficit hyperactivity disorder, conduct disorder, oppositional defiant disorder; early anxiety disorders—separation anxiety disorder, overanxious disorder, specific phobias (animals), social phobia; late anxiety disorders—generalized anxiety disorder, panic, agoraphobia, specific phobias (excl. animals); mood disorders—major depression disorder, dysthymia, bipolar disorders; substance disorders—alcohol, cannabis, other illicit drug abuse/dependence