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Table 1 Baseline characteristics (n = 908)

From: The XN-30 hematology analyzer for rapid sensitive detection of malaria: a diagnostic accuracy study

 

Children

Adults

0–2 years

2–5 years

5–15 years

> 15 years

n = 266

n = 180

n = 127

n = 335

 

Median (IQR)

Median (IQR)

Median (IQR)

Median (IQR)

Age distribution (months, years)

12 (8–17) months

36 (28–46) months

8 (6–10) years

41 (29–59) years

Male: female ratio

1.5

1.5

1.3

1.2

Fever (days)

3 (2–3)

3 (2–3)

3 (2–4)

3 (2–4)

Temperature (°C)

38.5 (38.0–39.4)

38.3 (37.9–39.4)

38.2 (37.7–39.0)

38.3 (38.0–39.0)

Systolic BP (mm/Hg)

98 (89–106)

98 (90–108)

102 (95–112)

108 (96–124)

Diastolic BP (mm/Hg)

61 (53–65)

62 (56–69)

63 (59–75)

66 (60–76)

MAP (mm/Hg)

73 (66–79)

75 (67–81)

80 (72–87)

83 (72–92)

Pulse (min)

125 (112–133)

123 (108–135)

116 (100–125)

104 (96–119)

Respiratory rate (min)

35 (32–42)

32 (30–38)

29 (26–30)

27 (26–28)

Hemoglobin (g/dL)

7.8 (5.6–10.0)

8.6 (6.5–10.7)

9.4 (7.8–11.6)

10.3 (8.4–12.8)

WBC (cells Ă— 103/μL)

13.1 (10.0–19.4)

11.2 (7.9–16.5.)

10.6 (7.4–16.6)

7.9 (5.5–12.8)

Platelets (cells Ă— 103/μL)

277 (124–452)

232 (126–358)

271 (181–372)

237 (156–337)

 

n (%)

n (%)

n (%)

n (%)

Antimalarials taken in past 2 weeks

93 (34.2)

83 (46.1)

54 (42.1)

86 (25.8)

HIV (confirmed before inclusion)

1 (0.4)

2 (1.1)

3 (2.3)

11 (3.3)

Malnourished1

112 (43.4)

70 (41.2)

47 (41.6)

84 (28.6)

Severe anaemia2

87 (32.7)

50 (27.8)

33 (25.8)

72 (27.7)

Severe malaria

56 (21.0)

47 (26.1)

12 (9.3)

5 (1.5)

Severe anemia

28 (50.0)

15 (31.9)

8 (66.7)

4 (80.0)

Cerebral malaria

8 (14.3)

10 (21.3)

3 (25.0)

0

Respiratory distress

2 (3.6)

4 (8.5)

0

0

Parasitemia > 150.000 p/μL

18 (32.1)

18 (38.3)

1 (8.3)

1 (20.0)

  1. BP blood pressure, MAP mean arterial pressure, WBC white blood cells
  2. 1Based on Z-scores for children < 5 and BMI for older patients, data available for respectively 258, 170, 113, and 294 patients per age group
  3. 2Based on WHO criteria for severe anemia