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Table 1 Baseline characteristics (n = 908)

From: The XN-30 hematology analyzer for rapid sensitive detection of malaria: a diagnostic accuracy study

  Children Adults
0–2 years 2–5 years 5–15 years > 15 years
n = 266 n = 180 n = 127 n = 335
  Median (IQR) Median (IQR) Median (IQR) Median (IQR)
Age distribution (months, years) 12 (8–17) months 36 (28–46) months 8 (6–10) years 41 (29–59) years
Male: female ratio 1.5 1.5 1.3 1.2
Fever (days) 3 (2–3) 3 (2–3) 3 (2–4) 3 (2–4)
Temperature (°C) 38.5 (38.0–39.4) 38.3 (37.9–39.4) 38.2 (37.7–39.0) 38.3 (38.0–39.0)
Systolic BP (mm/Hg) 98 (89–106) 98 (90–108) 102 (95–112) 108 (96–124)
Diastolic BP (mm/Hg) 61 (53–65) 62 (56–69) 63 (59–75) 66 (60–76)
MAP (mm/Hg) 73 (66–79) 75 (67–81) 80 (72–87) 83 (72–92)
Pulse (min) 125 (112–133) 123 (108–135) 116 (100–125) 104 (96–119)
Respiratory rate (min) 35 (32–42) 32 (30–38) 29 (26–30) 27 (26–28)
Hemoglobin (g/dL) 7.8 (5.6–10.0) 8.6 (6.5–10.7) 9.4 (7.8–11.6) 10.3 (8.4–12.8)
WBC (cells × 103/μL) 13.1 (10.0–19.4) 11.2 (7.9–16.5.) 10.6 (7.4–16.6) 7.9 (5.5–12.8)
Platelets (cells × 103/μL) 277 (124–452) 232 (126–358) 271 (181–372) 237 (156–337)
  n (%) n (%) n (%) n (%)
Antimalarials taken in past 2 weeks 93 (34.2) 83 (46.1) 54 (42.1) 86 (25.8)
HIV (confirmed before inclusion) 1 (0.4) 2 (1.1) 3 (2.3) 11 (3.3)
Malnourished1 112 (43.4) 70 (41.2) 47 (41.6) 84 (28.6)
Severe anaemia2 87 (32.7) 50 (27.8) 33 (25.8) 72 (27.7)
Severe malaria 56 (21.0) 47 (26.1) 12 (9.3) 5 (1.5)
Severe anemia 28 (50.0) 15 (31.9) 8 (66.7) 4 (80.0)
Cerebral malaria 8 (14.3) 10 (21.3) 3 (25.0) 0
Respiratory distress 2 (3.6) 4 (8.5) 0 0
Parasitemia > 150.000 p/μL 18 (32.1) 18 (38.3) 1 (8.3) 1 (20.0)
  1. BP blood pressure, MAP mean arterial pressure, WBC white blood cells
  2. 1Based on Z-scores for children < 5 and BMI for older patients, data available for respectively 258, 170, 113, and 294 patients per age group
  3. 2Based on WHO criteria for severe anemia