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Table 4 Prevalence of disease on qPCR, N (%, 95% CI) *McNemar test to compare sensitivity and specificity present. All ratios presented as XN-30 relative to microscopy

From: The XN-30 hematology analyzer for rapid sensitive detection of malaria: a diagnostic accuracy study

  XN-30 and microscopy versus qPCR results (n = 837)
XN-30 Microscopy Test ratio (95% CI) p value
  Positive Negative Positive Negative   
qPCR > 0.05 p/μL 253 104 237 120   
qPCR < 0.05 p/μL 2 478 0 480   
Sensitivity 70.9%   66.4%   0.94 (0.90–0.97) .0009
Specificity 99.6%   100.0%   0 .5
PPV 98.9%   100.0%    
NPV 83.4%   80.0%    
ROC 0.86   0.83    
  1. qPCR qualitative polymerase chain reaction, PPV positive predictive value, NPV negative predictive value