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Table 3 Performance of serological markers for a diagnosis of celiac disease

From: Celiac disease: a comprehensive current review

  Sensitivity (%) Specificity (%) PPV (%) NPV (%) Diagnostic accuracy (%)
Anti-tTG IgA 96.8 91.0 91.2 96.8 97.7
EmA IgA 93.7 100 100 94.4 96.9
DGP IgG 84.4 98.5 98.2 86.8 91.6
  1. Anti-tTG anti-transglutaminase antibodies, DGP direct antibodies against deamidated gliadin peptides, EmA anti-endomysium antibodies, NPV negative predictive value, PPV positive predictive value