Baseline | All individuals with 25(OH)D measured | Individuals with genetic data | |||
---|---|---|---|---|---|
Characteristic | CKB | CGPS | CCHS | CKB | CGPS |
Demographic | (n = 13,565) | (n = 25,621) | (n = 10,271) | (n = 82,464) | (n = 106,911) |
Age (SD), years | 53.2 (11.2) | 58.5 (13.0) | 56.7 (11.9) | 51.4 (10.6) | 58.0 (13.1) |
Women, % | 49.2 | 54.9 | 55.7 | 60.5 | 55 |
Current smoker, % | 47.2 | 20.5 | 58.4 | 36.9 | 17.1 |
Current drinker, % | 56.8 | 88.3 | 69 | 53.7 | 89.1 |
Low physical activity* | 18.15 | 6.8 | 16.8 | 18.15 | 6.2 |
BMI (SD), kg/m2 | 23.6 (3.5) | 26.1 (4.3) | 25.3 (4.2) | 23.7 (3.4) | 26.1 (4.3) |
SBP (SD), mmHg | 140.2 (25.9) | 141.1 (21.1) | 140.5 (21.6) | 131.2 (21.3) | 141.6 (21.4) |
DBP (SD), mmHg | 82.2 (14.5) | 83.9 (11.4) | 85.1 (12.1) | 77.8 (11.2) | 84.3 (11.5) |
Doctor diagnosed prior disease, % | |||||
Heart disease | 0 | 6.1 | 3.5 | 3 | 5.8 |
Stroke | 0 | 1.4 | 1 | 1.8 | 1.3 |
Hypertension | 15.9 | 60.9 | 56.1 | 11.5 | 60.3 |
Diabetes | 3.7 | 4.5 | 3.3 | 3.2 | 4.2 |
Cancer | 0 | 6.5 | 4 | 0.5 | 6.9 |
Current medication, % | |||||
Statin use | 0 | 11.6 | NA | 0.2 | 12.1 |
Aspirin use | 1.3 | 12.7 | NA | 1.1 | 11.7 |
Blood pressure lowering | 6.1 | 20.3 | 10.8 | 4.8 | 19.8 |
Plasma 25(OH)D (SD), nmol/L | 83.7 (26.6) | 55.3 (26.0) | 44.3 (24.1) | 83.4 (26.2) | 55.3 (26.1) |