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Table 1 Characteristics for all individuals with 25(OH)D measured or with genetic data

From: Vitamin D and cause-specific vascular disease and mortality: a Mendelian randomisation study involving 99,012 Chinese and 106,911 European adults

Baseline All individuals with 25(OH)D measured Individuals with genetic data
Characteristic CKB CGPS CCHS CKB CGPS
Demographic (n = 13,565) (n = 25,621) (n = 10,271) (n = 82,464) (n = 106,911)
 Age (SD), years 53.2 (11.2) 58.5 (13.0) 56.7 (11.9) 51.4 (10.6) 58.0 (13.1)
 Women, % 49.2 54.9 55.7 60.5 55
 Current smoker, % 47.2 20.5 58.4 36.9 17.1
 Current drinker, % 56.8 88.3 69 53.7 89.1
 Low physical activity* 18.15 6.8 16.8 18.15 6.2
 BMI (SD), kg/m2 23.6 (3.5) 26.1 (4.3) 25.3 (4.2) 23.7 (3.4) 26.1 (4.3)
 SBP (SD), mmHg 140.2 (25.9) 141.1 (21.1) 140.5 (21.6) 131.2 (21.3) 141.6 (21.4)
 DBP (SD), mmHg 82.2 (14.5) 83.9 (11.4) 85.1 (12.1) 77.8 (11.2) 84.3 (11.5)
Doctor diagnosed prior disease, %
 Heart disease 0 6.1 3.5 3 5.8
 Stroke 0 1.4 1 1.8 1.3
 Hypertension 15.9 60.9 56.1 11.5 60.3
 Diabetes 3.7 4.5 3.3 3.2 4.2
 Cancer 0 6.5 4 0.5 6.9
Current medication, %
 Statin use 0 11.6 NA 0.2 12.1
 Aspirin use 1.3 12.7 NA 1.1 11.7
 Blood pressure lowering 6.1 20.3 10.8 4.8 19.8
 Plasma 25(OH)D (SD), nmol/L 83.7 (26.6) 55.3 (26.0) 44.3 (24.1) 83.4 (26.2) 55.3 (26.1)
  1. CKB the China Kadoorie Biobank, CGPS the Copenhagen General Population Study, CCHS the Copenhagen City Heart Study, SD standard deviation, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure
  2. *Self-reported passivity or less than 2 h of light physical activity a week in CGPS and CCHS; MET-h/day < 8.4 (the bottom quintile) in CKB
  3. A total of 3397 individuals in the genetic study in CKB had plasma 25(OH)D concentrations measured
  4. 25(OH)D: 1 ng/ml = 2.496 nmol/L