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Table 1 Characteristics of the primary qualitative reports

From: The research burden of randomized controlled trial participation: a systematic thematic synthesis of qualitative evidence

 

N = 45 (100.0%)

Primary qualitative report characteristics

 Study design

  Qualitative

37 (82.2%)

  Mixed methods

8 (17.8%)

 Data collection methods

  Interviews

39 (86.6%)

  Focus groups

3 (6.7%)

  Surveys with open-ended questions

3 (6.7%)

 Data analysis methods

  Content analysis

9 (20.0%)

  Thematic analysis

21 (46.7%)

  Grounded theory

11 (24.4%)

  Interpretive phenomenological analysis

2 (4.4%)

  Not reported

2 (4.4%)

 For a single qualitative study, the RCT participants were sourced from:

  1 RCT**

31 (71.1%)

  Multiple RCTs**

8 (15.5%)

  Not reported***

6 (13.3%)

 Number of RCT participants in each qualitative study

  Median (Q1, Q3); n

21.0 (15, 38); 1732

 Was the primary qualitative study nested in the RCTs?

  Yes

27 (60.0%)

 Clinical domain

  Oncology

14 (31.1%)

  Chronic diseases

12 (26.7%)

  Acute illnesses

4 (8.9%)

  Mental health

1 (2.2%)

  Trauma/orthopedics

2 (4.4%)

  Obstetrics

8 (17.8%)

  Urogynecology

2 (4.4%)

  Mixed

2 (4.4%)

 Publication year of primary qualitative study

  Before 2005

6 (13.3%)

CASP Tool Quality Appraisal

Yes

 Q1 Was there a clear statement of the aims of the research?

45 (100.0%)

 Q2 Is a qualitative methodology appropriate?

45 (100.0%)

 Q3 Was the research design appropriate to address the aims of the research?

45 (100.0%)

 Q4 Was the recruitment strategy appropriate to the aims of the research?

36 (80.0%)

 Q5 Was the data collected in a way that addressed the research issue?

17 (37.8%)

 Q6 Has the relationship between researcher and participants been adequately considered?

15 (33.3%)

 Q7 Have ethical issues been taken into consideration?

42 (93.3%)

 Q8 Was the data analysis sufficiently rigorous?

26 (57.8%)

 Q9 Is there a clear statement of findings?

45 (100.0%)

  1. *Due to rounding off numbers may not add up to 100
  2. **31 qualitative studies involved a single RCT, and we were able to retrieve 27 RCT reports or protocols. 8 qualitative studies sourced participants from a total of 50 different RCTs, and we retrieved 15 RCT reports or protocols. Thus, a total of 42 RCT reports were available for description
  3. ***6 qualitative studies did not clearly report the number of RCTs that were involved