Table 4 Cox proportional hazards regression models of the age- and sex-adjusted associations between protein-adjusted serum free thiols and the risk of (A) cardiovascular events and (B) all-cause mortality in participants with and without a history of cardiovascular disease (CVD)

 Total cohort

0.71 (0.51–0.97), P = 0.031

1.00 (reference)

0.94 (0.75–1.19), P = 0.600

0.82 (0.63–1.07), P = 0.135

 No history of CVD

0.77 (0.54–1.08), P = 0.127

1.00 (reference)

0.96 (0.75–1.23), P = 0.761

0.83 (0.62–1.09), P = 0.181

 History of CVD

0.52 (0.23–1.19), P = 0.120

1.00 (reference)

0.82 (0.42–1.61), P = 0.567

0.84 (0.38–1.86), P = 0.670

 Total cohort

0.71 (0.50–1.01), P = 0.056

1.00 (reference)

0.77 (0.59–1.00), P = 0.048

0.73 (0.54–1.00), P = 0.049

 No history of CVD

0.80 (0.54–1.18), P = 0.253

1.00 (reference)

0.81 (0.61–1.09), P = 0.159

0.81 (0.58–1.12), P = 0.206

 History of CVD

0.47 (0.22–1.02), P = 0.055

1.00 (reference)

0.48 (0.24–0.96), P = 0.038

0.40 (0.16–0.99), P = 0.047