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Table 1 Linear regression analyses of SOrT scores on sociodemographic and clinical predictor variables in the MARS sample

From: Psychotherapy or medication for depression? Using individual symptom meta-analyses to derive a Symptom-Oriented Therapy (SOrT) metric for a personalised psychiatry

 

HAM-D SOrT metric outcome

BDI SOrT metric outcome

 

Unadjusted

Adjusted†

Unadjusted

Adjusted†

Predictor variable

Beta (SE)

p

Beta (SE)

p

Beta (SE)

p

Beta (SE)

p

Sociodemographic

 Female sex

0.125 (0.054)

0.021

0.044 (0.032)

0.167

− 0.084 (0.103)

0.414

− 0.173 (0.097)

0.075

 Age

> 0.001 (0.002)

0.983

− 0.001 (0.001)

0.631

0.007 (0.004)

0.074

0.008 (0.003)

0.027

 Married

0.025 (0.055)

0.648

− 0.045 (0.033)

0.176

− 0.103 (0.105)

0.328

−0.035 (0.099)

0.725

 Education: German A-levels

−0.136 (0.055)

0.014

− 0.025 (0.034)

0.447

0.035 (0.106)

0.742

0.109 (0.100)

0.276

Clinical

 Baseline HAM-D sum-score

0.075 (0.003)

< 0.001

–

–

0.021 (0.009)

0.017

− 0.002 (0.009)

0.815

 Baseline BDI sum-score

0.019 (0.002)

< 0.001

0.004 (0.002)

0.022

0.036 (0.005)

< 0.001

–

–

 Discharge HAM-D sum-score

0.011 (0.005)

0.026

0.002 (0.003)

0.590

0.014 (0.010)

0.152

0.006 (0.009)

0.560

 Discharge BDI sum-score

0.006 (0.003)

0.087

0.002 (0.002)

0.443

0.011 (0.007)

0.087

− 0.003 (0.007)

0.620

 History of depression

− 0.011 (0.069)

0.869

0.049 (0.039)

0.214

0.082 (0.130)

0.526

− 0.069 (0.123)

0.576

 Weeks of hospitalisation

0.010 (0.004)

0.009

< 0.001 (0.002)

0.829

0.010 (0.007)

0.173

> − 0.001 (0.007)

0.891

 Anxiety (HAMA)

0.030 (0.003)

< 0.001

− 0.003 (0.003)

0.325

0.010 (0.006)

0.112

− 0.001 (0.006)

0.817

  1. Separate linear regression analyses were performed for each predictor variable. Model intercepts are not reported to simplify result interpretation. Binary predictor variables are termed in a way that makes dummy coding obvious (e.g. female sex: 0 = male, 1 = female). Abbreviation: HAMA Hamilton Anxiety Rating Scale. †Models were adjusted for respective (HAM-D or BDI) baseline symptom covariate