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Table 2 Evaluation of SOrT-based treatment allocation

From: Psychotherapy or medication for depression? Using individual symptom meta-analyses to derive a Symptom-Oriented Therapy (SOrT) metric for a personalised psychiatry

  

12-week HAM-D, mean (SD)

 

Method

Pre-registered

Optimal

Non-Optimal

p value†

HAM-D-based SOrT allocation

 Valence

Yes

–

–

–

 Median split

No

8.50 (6.41)

7.17 (5.86)

0.091

 Extreme groups

Yes

8.86 (6.65)

7.08 (5.85)

0.074

BDI-based SOrT allocation

 Valence

Yes

7.62 (6.55)

8.03 (5.97)

0.617

 Median split

No

7.63 (6.14)

8.09 (6.24)

0.563

 Extreme groups

Yes

7.01 (6.16)

7.66 (6.15)

0.510

  1. †p values are based on independent samples t tests