Effects of a physical activity program from diagnosis on cardiorespiratory fitness in children with cancer: a national non-randomized controlled trial

Table 3 Effects of the RESPECT activity program on cardiorespiratory fitness and physical function

	n	Baseline	n	3 months	n	6 months	Group (p)	Time (p)	Change over time between groups per week (mean, 95% CI)	Change over time between groups (p)
VO₂peak (mL/kg/min)
INT	38	27.4 ± 6.97	30	26.1 ± 6.1	34	29.6 ± 6.9	0.2830	0.1415	0.25 [0.07 to 0.43]	0.0062
CON	13	27.8 ± 8.3	13	23.8 ± 5.9	10	22.1 ± 5.8		0.0238
Max watt (W)
INT	38	107.6 ± 33.1	30	95.5 ± 34.9	30	112.6 ± 49.5	0.0438	0.0185	0.21 [0.07 to 0.35]	0.0038
CON	13	113.1 ± 63.8	13	90 ± 45.1	10	69 ± 27		0.0694
Sit-to-stand (reps)
INT	90	25.1 ± 6.4	74	24.2 ± 7.2	81	24.6 ± 8.1	< 0.0001	0.4960	0.04 [− 0.08 to 017]	0.5057
CON	26	18.0 ± 5.0	38	16.5 ± 6.8	28	17.6 ± 7.3		0.8919
Timed-up-and-go (s)
INT	85	4.0 ± 0.8	74	4.3 ± 1.1	82	4.1 ± 1.2	< 0.0001	0.3038	0.02 [− 0.09 to 0.04]*	0.4129
CON	27	5.5 ± 1.7	38	6.0 ± 1.9	27	6.4 ± 3.3
Right handgrip strength (kg)
INT	103	21.4 ± 11.4	90	19.3 ± 10.5	91	20.1 ± 11.4	0.3418	0.4085	− 0.01 [− 029 to 0.27]	0.9438
CON	28	17.1 ± 9.7	39	12.1 ± 8.2	30	12.7 ± 8.5		0.0711
Left handgrip strength (kg)
INT	104	20.0 ± 10.8	90	17.4 ± 10.2	90	18.5 ± 10.7	0.0032	0.0062	0.01 [−0.002 to 0.02]	0.1668
CON	28	16.6 ± 10.4	39	10.5 ± 7.6	30	12.0 ± 8.4		0.0466
Flamingo balance (hits)
INT	98	0 [0 to 7]	86	0 [0 to 18]	87	0 [0 to 16]	< 0.0001	< 0.0001		0.5846
CON	27	0 [0 to 13]	37	1 [0 to 26]	27	1 [0 to 26]		< 0.0001

VO₂peak, sit-to-stand, timed-up-and-go, and handgrip strength are reported in mean and standard deviation, and flamingo balance is reported in median and range. All analysis is adjusted for age, sex, and diagnosis (hematological versus oncological)
INT the intervention group, CON the control group
*The interaction effect in TUG is presented in percentages

ISSN: 1741-7015