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Table 3 Effects of the RESPECT activity program on cardiorespiratory fitness and physical function

From: Effects of a physical activity program from diagnosis on cardiorespiratory fitness in children with cancer: a national non-randomized controlled trial

  n Baseline n 3 months n 6 months Group (p) Time (p) Change over time between groups per week (mean, 95% CI) Change over time between groups (p)
VO2peak (mL/kg/min)
 INT 38 27.4 ± 6.97 30 26.1 ± 6.1 34 29.6 ± 6.9 0.2830 0.1415 0.25 [0.07 to 0.43] 0.0062
 CON 13 27.8 ± 8.3 13 23.8 ± 5.9 10 22.1 ± 5.8   0.0238   
Max watt (W)
 INT 38 107.6 ± 33.1 30 95.5 ± 34.9 30 112.6 ± 49.5 0.0438 0.0185 0.21 [0.07 to 0.35] 0.0038
 CON 13 113.1 ± 63.8 13 90 ± 45.1 10 69 ± 27   0.0694   
Sit-to-stand (reps)
 INT 90 25.1 ± 6.4 74 24.2 ± 7.2 81 24.6 ± 8.1 < 0.0001 0.4960 0.04 [− 0.08 to 017] 0.5057
 CON 26 18.0 ± 5.0 38 16.5 ± 6.8 28 17.6 ± 7.3   0.8919   
Timed-up-and-go (s)
 INT 85 4.0 ± 0.8 74 4.3 ± 1.1 82 4.1 ± 1.2 < 0.0001 0.3038 0.02 [− 0.09 to 0.04]* 0.4129
 CON 27 5.5 ± 1.7 38 6.0 ± 1.9 27 6.4 ± 3.3     
Right handgrip strength (kg)
 INT 103 21.4 ± 11.4 90 19.3 ± 10.5 91 20.1 ± 11.4 0.3418 0.4085 − 0.01 [− 029 to 0.27] 0.9438
 CON 28 17.1 ± 9.7 39 12.1 ± 8.2 30 12.7 ± 8.5   0.0711   
Left handgrip strength (kg)
 INT 104 20.0 ± 10.8 90 17.4 ± 10.2 90 18.5 ± 10.7 0.0032 0.0062 0.01 [−0.002 to 0.02] 0.1668
 CON 28 16.6 ± 10.4 39 10.5 ± 7.6 30 12.0 ± 8.4   0.0466   
Flamingo balance (hits)
 INT 98 0 [0 to 7] 86 0 [0 to 18] 87 0 [0 to 16] < 0.0001 < 0.0001   0.5846
 CON 27 0 [0 to 13] 37 1 [0 to 26] 27 1 [0 to 26]   < 0.0001   
  1. VO2peak, sit-to-stand, timed-up-and-go, and handgrip strength are reported in mean and standard deviation, and flamingo balance is reported in median and range. All analysis is adjusted for age, sex, and diagnosis (hematological versus oncological)
  2. INT the intervention group, CON the control group
  3. *The interaction effect in TUG is presented in percentages