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Table 2 Comparison of the cohort characteristics between three geographical regions

From: Does parity matter in women’s risk of dementia? A COSMIC collaboration cohort study

Characteristics

Total (N = 14,792)

Asia (N = 5920)

Europe (N = 6171)

Latin America (N = 2701)

Statistics*

F or χ2

P

Post hoc*

Age, mean ± SD, years

73.1 ± 7.9

71.4 ± 7.8

74.2 ± 8.0

74.0 ± 7.0

217.79

< 0.001

a < b, a < c

Educational level, %

    

1049.72

< 0.001

 ≤ 6 years or primary school or under

48.8

46.6

39.4

75.0

   

 7 to 12 years or secondary school

38.8

39.0

48.4

16.1

   

 >  12 years or tertiary school or above

12.5

14.4

12.2

12.2

   

Hypertension, %

66.5

55.7

71.2

79.2

569.22

< 0.001

a < b, a < c, b < c

Diabetes mellitus, %

17.3

16.6

12.7

29.5

375.205

< 0.001

a > b, a < c, b < c

Parity (continuous), mean ± SD

2.8 ± 2.2

3.0 ± 1.8

2.3 ± 1.6

3.8 ± 3.5

512.99

< 0.001

a > b, a < c, b < c

Parity (categorical), %

    

949.73

< 0.001

 

 0 (nulliparity)

9.8

4.5

14.3

11.2

   

 1 to 4

74.6

77.8

77.9

60.2

   

 ≥ 5 (grand multiparity)

15.6

17.8

7.8

28.6

   

Dementia prevalence, %

5.9

5.7

4.7

9.1

64.60

< 0.001

a < c, b < c

Dementia subtypes, %

    

54.14

< 0.001

 AD

4.0

3.1

4.1

4.8

   

 VD

0.6

0.7

0.5

0.9

   

 NAVD

1.4

0.4

0.9

3.3

   
  1. SD standard deviation, AD Alzheimer’s disease, VaD vascular dementia, NAVD non-Alzheimer non-vascular dementia
  2. *Continuous variables were compared using analysis of variance, and categorical variables were compared using the χ2 test. Post hoc comparisons were based on Scheffé’s theorem: a = Asia; b = Europe; c = Latin America
  3. Estimated using 9 cohorts providing data on dementia subtypes