From: Does parity matter in women’s risk of dementia? A COSMIC collaboration cohort study
Characteristics | Total (N = 14,792) | Asia (N = 5920) | Europe (N = 6171) | Latin America (N = 2701) | Statistics* | ||
---|---|---|---|---|---|---|---|
F or χ2 | P | Post hoc* | |||||
Age, mean ± SD, years | 73.1 ± 7.9 | 71.4 ± 7.8 | 74.2 ± 8.0 | 74.0 ± 7.0 | 217.79 | < 0.001 | a < b, a < c |
Educational level, % | 1049.72 | < 0.001 | – | ||||
≤ 6 years or primary school or under | 48.8 | 46.6 | 39.4 | 75.0 | |||
7 to 12 years or secondary school | 38.8 | 39.0 | 48.4 | 16.1 | |||
> 12 years or tertiary school or above | 12.5 | 14.4 | 12.2 | 12.2 | |||
Hypertension, % | 66.5 | 55.7 | 71.2 | 79.2 | 569.22 | < 0.001 | a < b, a < c, b < c |
Diabetes mellitus, % | 17.3 | 16.6 | 12.7 | 29.5 | 375.205 | < 0.001 | a > b, a < c, b < c |
Parity (continuous), mean ± SD | 2.8 ± 2.2 | 3.0 ± 1.8 | 2.3 ± 1.6 | 3.8 ± 3.5 | 512.99 | < 0.001 | a > b, a < c, b < c |
Parity (categorical), % | 949.73 | < 0.001 | |||||
0 (nulliparity) | 9.8 | 4.5 | 14.3 | 11.2 | |||
1 to 4 | 74.6 | 77.8 | 77.9 | 60.2 | |||
≥ 5 (grand multiparity) | 15.6 | 17.8 | 7.8 | 28.6 | |||
Dementia prevalence, % | 5.9 | 5.7 | 4.7 | 9.1 | 64.60 | < 0.001 | a < c, b < c |
Dementia subtypes,† % | 54.14 | < 0.001 | – | ||||
AD | 4.0 | 3.1 | 4.1 | 4.8 | |||
VD | 0.6 | 0.7 | 0.5 | 0.9 | |||
NAVD | 1.4 | 0.4 | 0.9 | 3.3 |