Table 4 The risk of all-cause dementia associated with parity
From: Does parity matter in women’s risk of dementia? A COSMIC collaboration cohort study
Parity | Number of subjects | Unadjusted model | Adjusted model I* | Adjusted model II† | ||||
|---|---|---|---|---|---|---|---|---|
Control | Dementia | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
0 (nulliparity) | 1368 | 84 | 1.25 (0.93–1.68) | 0.014 | 0.91 (0.66–1.25) | 0.560 | 0.92 (0.67–1.27) | 0.613 |
1 (primiparity) | 2096 | 103 | 1.00 [Reference] | 1.00 [Reference] | 1.00 [Reference] | |||
2 | 3923 | 181 | 0.94 (0.73–1.20) | 0.618 | 1.12 (0.86–1.46) | 0.397 | 1.13 (0.86–1.47) | 0.375 |
3 | 2819 | 161 | 1.16 (0.90–1.50) | 0.245 | 1.19 (0.91–1.57) | 0.206 | 1.19 (0.91–1.57) | 0.200 |
4 | 1652 | 103 | 1.27 (0.96–1.68) | 0.096 | 1.06 (0.79–1.44) | 0.690 | 1.07 (0.79–1.45) | 0.664 |
≥ 5 (grand multiparity) | 2061 | 241 | 2.38 (1.87–3.02) | < 0.001 | 1.47 (1.11–1.94) | 0.007 | 1.47 (1.10–1.94) | 0.007 |
5 to 9 | 1836 | 212 | 2.35 (1.84–3.00) | < 0.001 | 1.43 (1.08–1.90) | 0.012 | 1.44 (1.08–1.90) | 0.012 |
≥ 10 | 225 | 29 | 2.62 (1.70–4.05) | < 0.001 | 1.84 (1.11–3.06) | 0.019 | 1.86 (1.11–3.09) | 0.018 |