Table 1 Characteristics of study participants and their mothers
Characteristic | Maternal IPTp arm | p value | |
|---|---|---|---|
Monthly SP (N = 339) | Monthly DP (N = 339) | ||
Maternal characteristics at enrollment | |||
 Age in years, mean (SD) | 23.9 (5.9) | 23.9 (5.7) | 0.98 |
 Gravidity, n (%) | |||
  Primigravida | 86 (25.4%) | 73 (21.5) | 0.21 |
  Secundigravida | 72 (21.2%) | 90 (26.6) | |
  Multigravida | 181 (53.4%) | 176 (51.8) | |
 Gestation age categories, n (%) | |||
  12–16 weeks | 195 (57.5%) | 204 (60.2%) | 0.48 |
  > 16–20 weeks | 144 (42.5%) | 135 (39.8%) | |
 Parasite prevalence by microscopy, n (%) | 170 (50.2%) | 183 (54.0%) | 0.32 |
Maternal characteristics during pregnancy | |||
 Parasite prevalence by microscopya, n/N (%) | 828/2291 (36.1%) | 365/2324 (15.7%) | < 0.001 |
 Incidence of malaria (episodes/PPY) | 0.59 | 0.09 | < 0.001 |
Measures of placental malaria | |||
 Placental blood positive by microscopyb, n/N (%) | 29/326 (8.9%) | 1/331 (0.3%) | < 0.001 |
 Placental blood positive by LAMPc, n/N (%) | 71/320 (22.2%) | 7/329 (2.1%) | < 0.001 |
 Positive placental histologyd, n/N (%) | 199/327 (60.9%) | 93/329 (28.3%) | < 0.001 |
Characteristics of infants at birth | |||
 Preterm birth, n (%) | 27 (8.0%) | 17 (5.0%) | 0.12 |
 Gestation age in weeks, mean (SD) | 39.4 (1.9) | 39.6 (1.6) | 0.08 |
 Low birth weight, n (%) | 34 (10.0%) | 26 (7.7%) | 0.28 |
 Birth weight in grams, mean (SD) | 3052 (505) | 3023 (408) | 0.41 |
 Female sex, n (%) | 166 (49.0%) | 180 (53.1%) | 0.28 |