Fig. 5
From: In utero and childhood exposure to tobacco smoke and multi-layer molecular signatures in children
Box plots showing the change of child protein/metabolite levels compared to unexposed mothers (y-axis) by categories of dose and/or duration of exposure to SHS (x-axis), adjusted for sustained maternal smoking in pregnancy. Horizontal line in the middle of the boxes shows the mean difference in protein/metabolite levels with respect to the reference category of unexposed mothers. Boxes represent the protein/metabolite change ± standard error (SE), and vertical lines indicate extreme changes defined as ± 3 × SE. b Plasma PAI1 levels, b serum C9, c serum SM (OH) C16:1, and d serum PC ae C38:0