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Table 3 Detection rate (the detection rate was calculated as the number of individuals in whom colorectal lesions (i.e. cancer, advanced neoplasm or any neoplastic lesion) were detected in each study arm with respect to the number of patients in whom the corresponding lesions were identified at colonoscopy, if a threshold of ≥ 6 mm in size of lesions detected by either CTC or CCE was used to indicate the work-up colonoscopy) of colon capsule endoscopy and CT colonography, according to the intention-to-screen analysis

From: Colon capsule endoscopy versus CT colonography in FIT-positive colorectal cancer screening subjects: a prospective randomised trial—the VICOCA study

Colorectal lesion1

CCE

CTC

RR

95% CI

p value

Cancer

4 (100%)

8 (100%)

1

1.00–1.00

Advanced neoplasm2

43 (100%)

41 (93.1%)

1.07

0.99–1.16

0.08

Any neoplastic lesion3

74 (98.6%)

47 (81.0%)

1.22

1.07–1.38

0.002

  1. CCE colon capsule endoscopy, CTC CT colonography, RR relative risk, 95% CI 95% confidence interval
  2. 1Patients were classified according to the most advanced lesion
  3. 2Advanced neoplasm includes invasive cancer, advanced adenomas and advanced serrated lesions
  4. 3Any neoplastic lesion includes cancer, advanced and non-advanced adenomas, and advanced and non-advanced serrated lesions