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Fig. 3 | BMC Medicine

Fig. 3

From: Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions

Fig. 3

Adjusted association between smoking status and repetitive DNA methylation elements (a) and mean and median methylation levels of all CpGs present on the 450K beadchip (b). Dots represent the regression coefficients, and bars represent the 95% confidence intervals of the association between smoking status during pregnancy and methylation levels measured in 568 placental biopsies of the EDEN cohort. Results were adjusted for child sex, parity, education level, season of conception, study center, maternal body mass index before pregnancy, maternal age at delivery, gestational duration, paternal smoking status at conception, batch, plate and chip, and estimated cellular heterogeneity

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