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Table 1 Population characteristics of the 1330 women enrolled in the Boston Birth Cohort, stratified by preterm delivery subgroups

From: Postpartum plasma metabolomic profile among women with preeclampsia and preterm delivery: implications for long-term health

Variables

Term delivery

Preterm delivery (PTD) subgroupsa

mPTD + preeclampsia

mPTD only

sPTD

N

980

79

52

219

Maternal age (years), M ± SD

28.1 ± 6.6

31.1 ± 6.5**

30.2 ± 7.2

28.6 ± 6.4

Ethnicity

 African American

621 (63.4)

61 (77.2)

27 (51.9)

148 (67.6)

 White

40 (4.1)

2 (2.5)

2 (3.9)

12 (5.5)

 Hispanic

200 (20.4)

12 (15.2)

17 (32.7)

45 (20.5)

 Others

119 (12.1)

4 (5.1)

6 (11.5)

14 (6.4)

Maternal birthplace: non-US-born

620 (63.3)

50 (63.3)

33 (63.5)

115 (52.5)**

Married

338 (34.5)

26 (32.9)

17 (32.7)

54 (24.7)*

Pregestational BMI (kg/m2) category

 Normal

470 (48.0)

21 (26.6)**

16 (30.8)

104 (47.5)

 Overweight

258 (26.3)

24 (30.4)

17 (32.7)

62 (28.3)

 Obese

208 (21.2)

32 (40.5)

16 (30.8)

43 (19.6)

 Unknown

44 (4.5)

2 (2.5)

3 (5.8)

10 (4.6)

Highest education level

 < High school

273 (27.9)

12 (15.2)

21 (40.4)

62 (28.3)

 High school

362 (36.9)

39 (49.4)

18 (34.6)

86 (39.3)

 College or above

340 (34.7)

28 (35.4)

13 (25.0)

70 (32.0)

 Missing

5 (0.5)

0 (0.0)

0 (0.0)

1 (0.5)

Nulliparity

430 (43.9)

34 (43.0)

17 (32.7)

97 (44.3)

Maternal smoking during pregnancy

 Never

840 (85.7)

62 (78.5)

41 (78.8)

161 (73.5)***

 Quitter

64 (6.5)

8 (10.1)

3 (5.8)

20 (9.1)

 Current

64 (6.5)

8 (10.1)

8 (15.4)

38 (17.4)

 Unknown

12 (1.2)

1 (1.3)

0 (0.0)

0 (0.0)

 Alcohol drinking during pregnancy

73 (7.4)

3 (3.8)

5 (9.6)

20 (9.1)

Stress during lifetime

 Mild

410 (41.8)

29 (36.7)*

16 (30.8)

76 (34.7)

 Average

490 (50.0)

36 (45.6)

30 (57.7)

118 (53.9)

 Stressful

80 (8.2)

14 (17.7)

6 (11.5)

25 (11.4)

Chronic hypertension

37 (3.8)

28 (35.9)***

6 (11.5)*

12 (5.5)

Gestational diabetes

69 (7.0)

9 (11.4)

4 (7.7)

16 (7.3)

Pregestational diabetes

37 (3.8)

12 (15.2)***

4 (7.7)

12 (5.5)

Illicit drug use during pregnancy

66 (6.7)

9 (11.4)

6 (11.5)

34 (15.5)***

Mode of delivery, c-section

311 (31.8)

52 (65.8)***

42 (80.8)***

65 (29.7)

Infant’s sex, male

497 (50.7)

30 (38.0)*

31 (59.6)

123 (56.2)

  1. amPTD, medically indicated PTD; the “mPTD + preeclampsia” group refers to women with mPTD and preeclampsia (including preeclampsia, eclampsia, and hemolysis, elevated liver enzymes, and low platelet syndrome (HELLP)); sPTD, spontaneous preterm delivery
  2. *P < 0.05; **P < 0.01; ***P < 0.001 for the difference of population characteristics in women of different PTD subgroups compared to term controls, via ANOVA tests and chi-squared tests for continuous and categorical variables, respectively