Fig. 2
Brain regions associated with childhood trauma, genetic risk for higher BMI, and BMI. a The significant brain regions with GMV associated with both childhood abuse and BMI (marked by blue and pink), associated with both genetic risk and BMI (marked by green and pink), and the overlapped brain regions (i.e., brain regions associated with childhood abuse, genetic risk, and BMI, marked by pink) in male participants from the IMAGEN study. b, c The significant brain regions with GMV associated with variables mentioned above in male or female participants from the UK Biobank. Gray dotted line roughly marked the inner contour of the frontopolar cortex. GMV, gray matter volume; CA, childhood abuse; BMI, body mass index; PRSBMI, polygenic risk score for obesity