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Table 3 Predictive performance statistics for models in the individual IPPIC-UK cohorts with over 100 events

From: External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis

Model no.

Author (year)

Predictor

Sovio 2015 (4212 women)

Stirrup 2015 (54,635 women)

Ayorinde 2016 (136,635 women)

Poston 2006 (2422 women)

Fraser 2013 (14,344 women)

C-statistic (95% CI)

Calibration slope (95% CI)

CITL (95% CI)

C-statistic (95% CI)

Calibration slope (95% CI)

CITL (95% CI)

C-statistic (95% CI)

Calibration slope (95% CI)

CITL (95% CI)

C-statistic (95% CI)

Calibration slope (95% CI)

CITL (95% CI)

C-statistic (95% CI)

Calibration slope (95% CI)

CITL (95% CI)

Any-onset pre-eclampsia models

 4

Baschat 2014a

Clinical and biochemical

0.71 (0.67, 0.74)

1.24 (1.03, 1.44)

0.66 (0.53, 0.78)

            

 5

Goetzinger 2010

0.76 (0.73, 0.80)

1.71 (1.50, 1.91)

− 0.07 (− 0.20, 0.05)

            

 6

Odibo 2011a

0.78 (0.74, 0.81)

1.49 (1.33, 1.65)

− 0.03 (− 0.16, 0.09)

0.67 (0.65, 0.69)

0.96 (0.89, 1.04)

− 0.90 (− 0.95, − 0.85)

         

 8

Yu 2005a

Clinical and ultrasound

0.61 (0.57, 0.65)

0.08 (0.01, 0.14)

Not estimable

            

Early-onset pre-eclampsia models

 9

Baschat 2014b

Clinical

         

0.67 (0.63, 0.72)

1.28 (0.90, 1.66)

1.80 (1.63, 1.97)

   

 11

Kuc 2013a

   

0.64 (0.59, 0.68)

0.34 (0.23, 0.46)

− 4.51 (− 4.67, − 4.35)

0.68 (0.67, 0.70)

0.47 (0.43, 0.51)

− 3.39 (− 3.45, − 3.33)

      

Late-onset pre-eclampsia models

 18

Crovetto 2015b

Clinical

0.78 (0.75, 0.81)

1.25 (1.12, 1.38)

1.31 (1.18, 1.44)

            

 19

Kuc 2013b

0.60 (0.56, 0.64)

0.67 (0.45, 0.89)

− 1.49 (− 1.61, − 1.36)

0.64 (0.62, 0.65)

0.63 (0.56, 0.70)

− 1.97 (− 2.03, − 1.92)

0.84 (0.64 to 0.94)

0.75 (0.45, 1.04)

− 1.44 (− 2.09, − 0.79)

   

0.66 (0.62, 0.70)

0.76 (0.55, 0.97)

− 1.57 (− 1.70, − 1.45)

 24

Yu 2005c

Clinical and ultrasound

0.61 (0.57, 0.64)

0.08 (0.01, 0.15)

Not estimable

            
  1. CITL = Calibration-in-the-large