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Table 3 Predictive performance statistics for models in the individual IPPIC-UK cohorts with over 100 events

From: External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis

Model no. Author (year) Predictor Sovio 2015 (4212 women) Stirrup 2015 (54,635 women) Ayorinde 2016 (136,635 women) Poston 2006 (2422 women) Fraser 2013 (14,344 women)
C-statistic (95% CI) Calibration slope (95% CI) CITL (95% CI) C-statistic (95% CI) Calibration slope (95% CI) CITL (95% CI) C-statistic (95% CI) Calibration slope (95% CI) CITL (95% CI) C-statistic (95% CI) Calibration slope (95% CI) CITL (95% CI) C-statistic (95% CI) Calibration slope (95% CI) CITL (95% CI)
Any-onset pre-eclampsia models
 4 Baschat 2014a Clinical and biochemical 0.71 (0.67, 0.74) 1.24 (1.03, 1.44) 0.66 (0.53, 0.78)             
 5 Goetzinger 2010 0.76 (0.73, 0.80) 1.71 (1.50, 1.91) − 0.07 (− 0.20, 0.05)             
 6 Odibo 2011a 0.78 (0.74, 0.81) 1.49 (1.33, 1.65) − 0.03 (− 0.16, 0.09) 0.67 (0.65, 0.69) 0.96 (0.89, 1.04) − 0.90 (− 0.95, − 0.85)          
 8 Yu 2005a Clinical and ultrasound 0.61 (0.57, 0.65) 0.08 (0.01, 0.14) Not estimable             
Early-onset pre-eclampsia models
 9 Baschat 2014b Clinical           0.67 (0.63, 0.72) 1.28 (0.90, 1.66) 1.80 (1.63, 1.97)    
 11 Kuc 2013a     0.64 (0.59, 0.68) 0.34 (0.23, 0.46) − 4.51 (− 4.67, − 4.35) 0.68 (0.67, 0.70) 0.47 (0.43, 0.51) − 3.39 (− 3.45, − 3.33)       
Late-onset pre-eclampsia models
 18 Crovetto 2015b Clinical 0.78 (0.75, 0.81) 1.25 (1.12, 1.38) 1.31 (1.18, 1.44)             
 19 Kuc 2013b 0.60 (0.56, 0.64) 0.67 (0.45, 0.89) − 1.49 (− 1.61, − 1.36) 0.64 (0.62, 0.65) 0.63 (0.56, 0.70) − 1.97 (− 2.03, − 1.92) 0.84 (0.64 to 0.94) 0.75 (0.45, 1.04) − 1.44 (− 2.09, − 0.79)     0.66 (0.62, 0.70) 0.76 (0.55, 0.97) − 1.57 (− 1.70, − 1.45)
 24 Yu 2005c Clinical and ultrasound 0.61 (0.57, 0.64) 0.08 (0.01, 0.15) Not estimable             
  1. CITL = Calibration-in-the-large