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Table 1 Baseline characteristics of participants who were still alive vs those who were deceased by December 31, 2015

From: Relationship between serum B12 concentrations and mortality: experience in NHANES

  

Still alive, N = 21,239

Deceased, N = 3023

p value

Gender, M/F (n)

24,262

10,449/10,790

1712/1311

2.0 × 10−14

Age 18–39 years (%)

24,262

41.7

6.0

< 1.0 × 10−200

Age 40–59 years (%)

 

32.9

14.3

Age ≥ 60 years (%)

 

25.4

79.7

Body mass index (kg/m2)

23,920

28.6 ± 6.7

28.0 ± 6.2

8.8 × 10−7

Waist circumference (cm)

23,245

97 ± 16

100 ± 15

2.0 × 10−18

SBP (mmHg)

23,298

123 ± 18

138 ± 25

< 1.0 × 10−200

DBP (mmHg)

23,118

71 ± 11

69 ± 13

2.4 × 10−17

WBC (× 109/l)

24,235

7.2 ± 2.2

7.4 ± 3.3

2.1 × 10−10

Hemoglobin (mg/dl)

24,235

14.2 ± 1.5

14.0 ± 1.7

1.5 × 10−15

C-reactive protein (mg/dl)

14,174

0.19 (0.07–0.44)

0.29 (0.14–0.67)

3.9 × 10−70

Cholesterol (mmol/l)

24,138

5.0 ± 1.1

5.1 ± 1.2

2.5 × 10−7

Glucose (mmol/l)

24,141

5.5 ± 2.0

6.2 ± 2.8

1.8 × 10−63

HbA1c (%)

24,225

5.6 ± 1.0

6.0 ± 1.3

9.7 × 10−77

Creatinine (μmol/l)

24,141

72 (62–88)

80 (71–106)

8.7 × 10−80

eGFR (ml/min/1.73 m2)

24,141

100 (84–116)

77 (56–94)

< 1.0 × 10−200

Serum B12 (pmol/l)

24,262

343 (257–463)

354 (252–494)

0.016

Serum folate (nmol/l)

24,182

38.7 (27.4–53.4)

37.7 (32.7–69.9)

8.4 × 10−89

Methylmalonic acid (nmol/l)1

19,492

130 (100–172)

175 (126–252)

4.9 × 10−158

Homocysteine (μmol/l)2

13,681

7.7 (6.4–9.3)

10.4 (8.3–13.3)

< 1.0 × 10−200

Ethnicity

24,262

  

3.5 × 10−71

 Mexican American (n)

 

3927

568

 Other Hispanic (n)

 

1433

90

 Non-Hispanic White (n)

 

9077

1730

 Non-Hispanic Black (n)

 

4811

543

 Others, including multi-racial (n)

 

1991

92

Education

22,730

  

1.8 × 10−166

 Level 1 (%)

 

10.4

25.2

 Level 2 (%)

 

14.4

19.7

 Level 3 (%)

 

22.9

23.4

 Level 4 (%)

 

29.5

20.2

 Level 5 (%)

 

22.8

11.5

Annual family income

22,348

  

1.9 × 10−110

 < 25k (%)

 

36.3

56.0

 25–75k (%)

 

41.3

36.5

 > 75k (%)

 

22.4

7.5

Never smoking (%)

23,179

51.7

39.9

3.0 × 10−33

Former smoking (%)

24,262

19.4

35.5

7.8 × 10−90

Current smoking (%)

24,262

26.5

24.0

0.003

Diabetes diagnosis (%)

24,262

14.1

29.0

1.0 × 10−97

Hypertension diagnosis (%)

24,262

30.6

60.3

2.4 × 10−226

Lipid diagnosis (%)

24,262

29.0

40.3

9.5 × 10−37

CVD diagnosis (%)

24,262

7.4

33.3

< 1.0 × 10−300

Cancer diagnosis (%)

24,262

6.5

19.4

3.3 × 10−130

Lung diagnosis (%)

24,262

11.0

16.5

4.8 × 10−19

  1. Data are presented as mean ± SD, median (IQR), numbers or percentages
  2. 1In n = 19,492
  3. 2In n = 13,681