Table 4 Age-specific 10-year cumulative risk of breast cancer (%) by age at diagnosis of a first-degree relative with in situ or invasive breast cancer
Age of index woman (years) | Whole population | No family history* | Age of relative at breast cancer diagnosis (years) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
All ages | < 50 | ≥ 50 | ||||||||||||||
In situ | Invasive | In situ | Invasive | In situ | Invasive | |||||||||||
CR | 95% CI | CR | 95% CI | CR | 95% CI | CR | 95% CI | CR | 95% CI | CR | 95% CI | CR | 95% CI | CR | 95% CI | |
30 | 0.2 | 0.2–0.3 | 0.2 | 0.2–0.2 | 0.2 | 0.1–0.3 | 0.6 | 0.5–0.6 | 0.3 | 0.0–0.6 | 0.8 | 0.7–0.9 | 0.2 | 0.0–0.3 | 0.5 | 0.4–0.6 |
35 | 0.6 | 0.6–0.6 | 0.5 | 0.5–0.6 | 0.8 | 0.5–1.0 | 1.1 | 1.1–1.2 | 1.0 | 0.4–1.5 | 1.5 | 1.4–1.7 | 0.7 | 0.4–0.9 | 1.1 | 1.0–1.2 |
40 | 1.1 | 1.1–1.2 | 1.1 | 1.1–1.1 | 1.8 | 1.4–2.1 | 2.1 | 2.1–2.2 | 1.7 | 1.0–2.4 | 2.8 | 2.6–3.0 | 1.8 | 1.4–2.2 | 2.1 | 2.0–2.2 |
45 | 1.8 | 1.8–1.8 | 1.7 | 1.6–1.7 | 2.8 | 2.3–3.2 | 3.2 | 3.1–3.3 | 2.0 | 1.2–2.7 | 3.8 | 3.5–4.0 | 3.1 | 2.5–3.6 | 3.2 | 3.1–3.3 |
50 | 2.2 | 2.2–2.2 | 2.1§ | 2.0–2.1 | 3.4§ | 2.9–3.9 | 3.7 | 3.6–3.8 | 2.8 | 1.9–3.7 | 4.1 | 3.9–4.4 | 3.6 | 3.0–4.2 | 3.8 | 3.6–3.9 |
55 | 2.6 | 2.6–2.7 | 2.5 | 2.5–2.5 | 3.9 | 3.4–4.5 | 4.2 | 4.1–4.3 | 4.9 | 3.6–6.2 | 4.6 | 4.3–4.9 | 3.6 | 3.0–4.2 | 4.3 | 4.2–4.5 |
60 | 3.3 | 3.2–3.3 | 3.1 | 3.0–3.1 | 4.6 | 3.9–5.2 | 5.0 | 4.8–5.1 | 5.9 | 4.4–7.4 | 5.3 | 4.9–5.7 | 4.2 | 3.4–4.9 | 5.1 | 4.9–5.3 |
65 | 3.6 | 3.6–3.7 | 3.4 | 3.4–3.5 | 5.2 | 4.4–6.0 | 5.6 | 5.4–5.7 | 5.8 | 4.2–7.5 | 6.1 | 5.6–6.6 | 4.9 | 4.0–5.9 | 5.6 | 5.4–5.8 |