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Table 1 Epidemiological parameters

From: Modelling the household-level impact of a maternal respiratory syncytial virus (RSV) vaccine in a high-income setting

Notation

Description

Selection method

Baseline value (alternative values)

Reference

 

Vaccine coverage

Fixed

70% (30%, 50%, 100%)

[33,34,35,36,37]

1/ρV

Mean duration of protection after birth (from vaccination) in days

Calculated based on number of days of mother’s immunity remaining at birth

90 (182, 230) days. See text for explanation.

[9, 10]

1/ρI

Mean duration of protection after birth (from infection) in days

Calculated based on number of days of mother’s immunity remaining at birth

90 (182, 230) days. See text for explanation.

 

aV

Reduced susceptibility to infection in infant from mother having been vaccinated

Fixed + sensitivity analysis

0.4 (0.2, 0.6)

 

aI

Reduced susceptibility to infection in infant from mother having been infected

Fixed + sensitivity analysis

0.4 (0.2, 0.6)

[17]

1/σ

Latent period (days)

Gamma distribution, shape parameter 3

4

[38, 39]

1/γ

Infectious period (days)

Gamma distribution, shape parameter 3

9

[39, 40]

1/νI

Duration of immunity following infection

Gamma distribution, shape parameter 3

Mean 230 days (182, 364)

[41]

1/νV

Duration of immunity following vaccination

Gamma distribution, shape parameter 3

Mean 230 days (182, 364)

 

ω

Reduced infectiousness in individuals aged 10 years and over

Calibration

0.2

See text

q

Community transmission coefficient

Calibration

0.015

See text

qh

Household transmission coefficient

Calibration

2.4

See text

b1

Amplitude of seasonal forcing

Fixed

0.397

[17]