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Fig. 3 | BMC Medicine

Fig. 3

From: Serum keratin 19 (CYFRA21-1) links ductular reaction with portal hypertension and outcome of various advanced liver diseases

Fig. 3

Serum CYFRA21-1 as an indicator of long-term death and HCC occurrence in patients with alcoholic cirrhosis (cohort iii). Two hundred thirty-one patients with cirrhosis due to long-term alcohol misuse (median follow-up of 73 months) were analyzed. The median serum CYFRA21-1 value was used to generate Kaplan-Meier curves (CYFRA21-1 < 5.26 ng/mL in blue, CYFRA21-1 ≥ 5.26 ng/mL in red) for the following outcomes: a the overall transplantation-free survival, b the liver-related, not HCC-related transplantation-free survival, and c the occurrence of HCC. Unadjusted hazard ratios (HRs) with their 95% confidence intervals [in brackets] and log-rank P values are shown in the corresponding graphs

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