Fig. 2
Manhattan plots for the 4 tag SNPs for ABO blood group antigens with all phenotypes included by category. The horizontal axis shows the phenotypes by category, and the vertical axis shows the -log10 transformed P values. The blue line indicates the corrected statistical significance level, P = 3.2 × 10− 6. The categories of phenotypes (from left to right on the x-axis) are blood biochemistry, circulatory, blood count, digestive, endocrine, neoplasms, other categories, physical measures, respiratory, and symptoms, respectively. Other categories include dermatologic, genitourinary, gynecologic and obstetric, hematopoietic, infectious diseases, injuries and poisonings, mental health, musculoskeletal, neurological, sense organs, and others. a Manhattan plot for rs507666 (A1 blood group antigen). b Manhattan plot for rs8176704 (A2 blood group antigen). c Manhattan plot for rs8176746 (B blood group antigen). d Manhattan plot for rs687289 (O blood group antigen)