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Table 2 Association between cannabis use disorder and future cardiovascular hospitalization

From: Cannabis use disorder and the future risk of cardiovascular disease in parous women: a longitudinal cohort study

 

Total no. women

No. women with cardiovascular hospitalizations

Incidence per 10,000 person years (95% confidence interval)

Hazard ratio (95% confidence interval)

Unadjusted

Adjusteda

Cannabis use disorder

 Yes

3472

169

58.4 (50.2–67.8)

2.75 (2.36–3.20)

1.48 (1.27–1.72)

 No

1,243,563

63,754

33.6 (33.3–33.9)

Referent

Referent

Comorbid substance use

 Cannabis with other substance use

1823

118

75.0 (62.7–89.9)

3.44 (2.87–4.13)

1.84 (1.53–2.21)

 Cannabis alone

1649

51

38.5 (29.3–50.7)

1.97 (1.50–2.58)

1.30 (0.99–1.72)

 Other substance use alone

11,665

1115

80.0 (75.5–84.9)

2.91 (2.74–3.09)

1.81 (1.69–1.94)

 No substance use

1,231,898

62,639

33.3 (33.0–33.5)

Referent

Referent

Timing of cannabis use

 During pregnancy

1618

67

50.1 (39.5–63.7)

2.40 (1.88–3.05)

1.65 (1.29–2.10)

 Before pregnancy

1854

102

65.4 (53.9–79.4)

3.05 (2.51–3.71)

1.38 (1.14–1.68)

 No cannabis use

1,243,563

63,754

33.6 (33.3–33.9)

Referent

Referent

  1. aAdjusted for age, gravidity, mental illness, tobacco use, comorbidity, socioeconomic deprivation, place of residence, and time period