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Table 2 Association between cannabis use disorder and future cardiovascular hospitalization

From: Cannabis use disorder and the future risk of cardiovascular disease in parous women: a longitudinal cohort study

  Total no. women No. women with cardiovascular hospitalizations Incidence per 10,000 person years (95% confidence interval) Hazard ratio (95% confidence interval)
Unadjusted Adjusteda
Cannabis use disorder
 Yes 3472 169 58.4 (50.2–67.8) 2.75 (2.36–3.20) 1.48 (1.27–1.72)
 No 1,243,563 63,754 33.6 (33.3–33.9) Referent Referent
Comorbid substance use
 Cannabis with other substance use 1823 118 75.0 (62.7–89.9) 3.44 (2.87–4.13) 1.84 (1.53–2.21)
 Cannabis alone 1649 51 38.5 (29.3–50.7) 1.97 (1.50–2.58) 1.30 (0.99–1.72)
 Other substance use alone 11,665 1115 80.0 (75.5–84.9) 2.91 (2.74–3.09) 1.81 (1.69–1.94)
 No substance use 1,231,898 62,639 33.3 (33.0–33.5) Referent Referent
Timing of cannabis use
 During pregnancy 1618 67 50.1 (39.5–63.7) 2.40 (1.88–3.05) 1.65 (1.29–2.10)
 Before pregnancy 1854 102 65.4 (53.9–79.4) 3.05 (2.51–3.71) 1.38 (1.14–1.68)
 No cannabis use 1,243,563 63,754 33.6 (33.3–33.9) Referent Referent
  1. aAdjusted for age, gravidity, mental illness, tobacco use, comorbidity, socioeconomic deprivation, place of residence, and time period