Table 3 Association of cannabis use disorder with specific cardiovascular outcomes
Cannabis use disorder | No cannabis use disorder | Hazard ratio (95% confidence interval)a | |||
|---|---|---|---|---|---|
No. events | Incidence per 10,000 person years | No. events | Incidence per 10,000 person years | ||
Cardiovascular disease | 161 | 55.5 | 62,256 | 32.8 | 1.08 (0.92–1.28) |
Heart | |||||
Heart failure | 10 | 3.4 | 3058 | 1.6 | 0.83 (0.43–1.58) |
Myocardial infarction | 9 | 3.0 | 5600 | 2.9 | 0.65 (0.33–1.26) |
Other ischemic heart disease | 23 | 7.7 | 10,046 | 5.2 | 1.00 (0.65–1.54) |
Angina | 5 | 1.7 | 2843 | 1.5 | 1.01 (0.41–2.51) |
Cardiac arrest | < 5 | 1.3 | 895 | 0.5 | 0.82 (0.29–2.37) |
Inflammatory heart disease | 11 | 3.7 | 960 | 0.5 | 1.37 (0.72–2.61) |
Conduction disorder | 33 | 11.1 | 11,526 | 6.0 | 1.15 (0.80–1.64) |
Valve disease | 11 | 3.7 | 2692 | 1.4 | 1.34 (0.72–2.50) |
Cardiomyopathy | < 5 | 1.3 | 1788 | 0.9 | 0.64 (0.23–1.81) |
Lungs | |||||
Pulmonary embolism | 22 | 7.4 | 4568 | 2.4 | 1.38 (0.88–2.16) |
Other pulmonary vascular disease | < 5 | 1.0 | 1236 | 0.6 | 0.67 (0.21–2.10) |
Cerebrovascular | |||||
Ischemic stroke | 10 | 3.4 | 2728 | 1.4 | 1.27 (0.65–2.48) |
Hemorrhagic stroke | 10 | 3.4 | 2199 | 1.1 | 2.08 (1.07–4.05) |
Other cerebrovascular disease | 8 | 2.7 | 2241 | 1.2 | 1.22 (0.59–2.51) |
Hypertension | 74 | 25.1 | 39,915 | 20.8 | 0.96 (0.75–1.21) |
Atherosclerosis | 15 | 5.0 | 7591 | 3.9 | 0.97 (0.57–1.65) |
Aortic aneurysm or dissection | < 5 | 0.7 | 360 | 0.2 | 4.61 (0.86–24.70) |
Aneurysm of other vessels | < 5 | 0.3 | 1597 | 0.8 | 0.22 (0.03–1.55) |
Arterial embolism | 5 | 1.7 | 1019 | 0.5 | 1.37 (0.55–3.43) |
Cardiovascular intervention | 38 | 12.8 | 11,557 | 6.0 | 1.46 (1.04–2.05) |
Heart procedure | 13 | 4.4 | 6361 | 3.3 | 1.09 (0.62–1.92) |
Vessel procedure | 10 | 3.4 | 2979 | 1.5 | 2.42 (1.21–4.87) |
Coronary care unit admission | 22 | 7.4 | 4616 | 2.4 | 1.58 (1.01–2.49) |