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Table 3 Association of cannabis use disorder with specific cardiovascular outcomes

From: Cannabis use disorder and the future risk of cardiovascular disease in parous women: a longitudinal cohort study

  Cannabis use disorder No cannabis use disorder Hazard ratio (95% confidence interval)a
No. events Incidence per 10,000 person years No. events Incidence per 10,000 person years
Cardiovascular disease 161 55.5 62,256 32.8 1.08 (0.92–1.28)
 Heart
  Heart failure 10 3.4 3058 1.6 0.83 (0.43–1.58)
  Myocardial infarction 9 3.0 5600 2.9 0.65 (0.33–1.26)
  Other ischemic heart disease 23 7.7 10,046 5.2 1.00 (0.65–1.54)
  Angina 5 1.7 2843 1.5 1.01 (0.41–2.51)
  Cardiac arrest < 5 1.3 895 0.5 0.82 (0.29–2.37)
  Inflammatory heart disease 11 3.7 960 0.5 1.37 (0.72–2.61)
  Conduction disorder 33 11.1 11,526 6.0 1.15 (0.80–1.64)
  Valve disease 11 3.7 2692 1.4 1.34 (0.72–2.50)
  Cardiomyopathy < 5 1.3 1788 0.9 0.64 (0.23–1.81)
 Lungs
  Pulmonary embolism 22 7.4 4568 2.4 1.38 (0.88–2.16)
  Other pulmonary vascular disease < 5 1.0 1236 0.6 0.67 (0.21–2.10)
 Cerebrovascular
  Ischemic stroke 10 3.4 2728 1.4 1.27 (0.65–2.48)
  Hemorrhagic stroke 10 3.4 2199 1.1 2.08 (1.07–4.05)
  Other cerebrovascular disease 8 2.7 2241 1.2 1.22 (0.59–2.51)
 Hypertension 74 25.1 39,915 20.8 0.96 (0.75–1.21)
 Atherosclerosis 15 5.0 7591 3.9 0.97 (0.57–1.65)
 Aortic aneurysm or dissection < 5 0.7 360 0.2 4.61 (0.86–24.70)
 Aneurysm of other vessels < 5 0.3 1597 0.8 0.22 (0.03–1.55)
 Arterial embolism 5 1.7 1019 0.5 1.37 (0.55–3.43)
Cardiovascular intervention 38 12.8 11,557 6.0 1.46 (1.04–2.05)
 Heart procedure 13 4.4 6361 3.3 1.09 (0.62–1.92)
 Vessel procedure 10 3.4 2979 1.5 2.42 (1.21–4.87)
 Coronary care unit admission 22 7.4 4616 2.4 1.58 (1.01–2.49)
  1. aAdjusted for age, gravidity, mental illness, other substance use, tobacco use, comorbidity, socioeconomic deprivation, place of residence, and time period