Table 2 Analysis of factors associated with mortality at 6 months

Methylprednisolone

0.584 (0.349–0.976)

0.040

0.547 (0.308–0.973)

0.040

 Centers ^a

–

0.683

 Cirrhosis

1.114 (0.566–2.194)

0.755

 Antiviral treatment ^a

–

0.410

 Male

0.594 (0.293–1.205)

0.149

 Age (years)

1.024 (1.004–1.045)

0.019

1.012 (0.987–1.037)

0.359

 Time from onset to admission (days)

1.008 (0.993–1.024)

0.304

 MELD score

1.123 (1.072–1.176)

0.000

 lg HBV DNA (IU/ml)

0.973 (0.851–1.112)

0.686

 HBV DNA positive

0.617 (0.313–1.218)

0.164

 HBeAg positive

0.726 (0.439–1.201)

0.213

 HBsAg

1.000 (1.000–1.000)

0.248

 ALT(U/L)

0.999 (0.999–1.000)

0.092

 AST(U/L)

1.000 (0.999–1.001)

0.859

Bilirubin (μmol/L)

1.004 (1.002–1.005)

0.000

1.003 (1.001–1.005)

0.004

 Albumin(g/L)

0.985 (0.924–1.050)

0.648

 Cholinesterase (IU/L)

1.000 (1.000–1.000)

0.893

 AFP (ng/ml)

0.999 (0.997–1.001)

0.228

Blood urea nitrogen (mmol/L)

1.149 (1.049–1.260)

0.003

1.195 (1.018–1.402)

0.029

 Creatinine (μmol/L)

1.006 (1.001–1.011)

0.020

0.995 (0.984–1.005)

0.318

 NH3(μg/dl)

1.002 (0.997–1.008)

0.413

 Triglyceride (mmol/L)

0.628 (0.401–0.986)

0.043

0.905 (0.524–1.561)

0.719

 Cholesterol (mmol/L)

0.835 (0.585–1.190)

0.319

 White blood cell(× 10⁹/L)

1.057 (0.986–1.133)

0.115

 Lymphocyte percentage

0.934 (0.903–0.966)

0.000

0.950 (0.883–1.023)

0.175

Monocyte percentage

1.103 (1.023–1.190)

0.011

1.149 (1.011–1.307)

0.034

 Lymphocyte to monocyte ratio

0.497 (0.366–0.674)

0.000

0.838 (0.468–1.502)

0.553

 Neutrophil percentage

1.037 (1.012–1.062)

0.003

 Procalcitonin (μg/L)

0.993 (0.871–1.132)

0.913

PTA (%)

0.942 (0.914–0.970)

0.000

0.931 (0.870–0.996)

0.038

 INR

2.272 (1.482–3.493)

0.000

0.918 (0.320–2.629)

0.873

 Red blood cell(× 10¹²/L)

0.959 (0.711–1.293)

0.782

 Hemoglobin(g/L)

0.998 (0.986–1.009)

0.702

 Platelet(× 10⁹/L)

0.996 (0.991–1.002)

0.163

 Ascites

2.021 (1.154–3.539)

0.014

0.879 (0.467–1.656)

0.690

 Infections

1.381 (0.826–2.308)

0.218

 Electrolyte disturbance

0.599 (0.217–1.651)

0.322

 HE

2.161 (1.148–4.066)

0.017

1.270 (0.629–2.564)

0.505

 Hypoalbuminemia

1.010 (0.537–1.900)

0.975

 HRS

4.296 (1.544–11.954)

0.005

1.013 (0.216–4.753)

0.987