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Fig. 1 | BMC Medicine

Fig. 1

From: A serological framework to investigate acute primary and post-primary dengue cases reporting across the Philippines

Fig. 1

Determining anti-DENV IgM and IgG seroprevalence among the study population. A1 Histogram of study population anti-DENV IgM panbio units. Red dash: Panbio® seroprevalence threshold (11 panbio units). A2 Mixture model of anti-DENV IgM panbio units with 3 components representing IgM seronegative, primary and post-primary subpopulations. A3 Modelled classification probability curves of being anti-DENV IgM seronegative or seropositive. Black dash: lowest IgM panbio unit with a classification probability of being seropositive>seronegative (9.9 panbio units). B1 Histogram of anti-DENV IgG panbio units stratified by active/non-active DENV status. Red dash: Panbio® seroprevalence threshold (22 panbio units). B2 Mixture model of anti-DENV IgG titres among non-active DENV cases with 2 components representing IgG seronegative and seropositive subpopulations. B3 Modelled classification probability curves of being anti-DENV IgG seronegative or seropositive. Black dash: lowest IgG panbio units with a classification probability of being seropositive>seronegative (2.2 panbio units)

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BMC Medicine

ISSN: 1741-7015

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