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Table 2 Univariable and multivariable linear regression analyses for log2 MMA

From: Methylmalonic acid, vitamin B12, renal function, and risk of all-cause mortality in the general population: results from the prospective Lifelines-MINUTHE study

  Univariable Multivariable
Model 1
Multivariable
Model 2
Std b P value Std b P value Std b P value
   Log2 vitamin B12 (pmol/L) − 0.424 < 0.001 − 0.434 < 0.001 1.131 0.08
    Log2 eGFR (mL/min/1.73 m2) − 0.189 < 0.001 − 0.162 < 0.001 0.689 0.048
    Log2 vitamin B12 × log2 eGFR − 1.796 0.01
Demographics
 Male sex 0.002 0.9 − 0.065 0.005 − 0.053 0.02
 Age (years) 0.093 < 0.001 0.050 0.04 0.034 0.2
 High education − 0.099 < 0.001 − 0.030 0.2
Medication
 Use of vitamin supplements − 0.069 0.007
  1. Model 1: R2 = 0.22; adjusted R2 = 0.22
  2. Model 2: R2 = 0.22; adjusted R2 = 0.21
  3. eGFR estimated glomerular filtration rate, MMA methylmalonic acid