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Fig. 3 | BMC Medicine

Fig. 3

From: Cost-effectiveness modelling to optimise active screening strategy for gambiense human African trypanosomiasis in endemic areas of the Democratic Republic of Congo

Fig. 3

Theoretical optimum strategy. Theoretical optimum strategy for the mean simulation of infection dynamics given a range of WTP values (horizontal axis). ac examine the impact of different treatment coverage (pt) on a the optimal screening coverage, b the optimal screening interval and c the optimal number of zero-detections required to stop screening, to achieve the highest NMB for given WTP. These results assume a village population of 1000 where the disease in endemic. df examine the impact of different assumptions about population size and endemicity on d the optimal screening coverage, e the optimal screening interval and f the optimal number of active zero-detections required to stop screening. The demography and disease endemicity assumptions are as follows: a population of population 1,000 where the disease is endemic (‘1000 (E)’), a village of population 1000 where only one person is initially infected (single infection, or ‘1000 (S)’), a village of population 250 where disease is endemic (‘250 (E)’), and a village of population 1000 where disease is endemic and there exists a small probability of infectious importations (‘1000 (I)’). We fix zr=1 for all simulations

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