Fig. 3From: Cost-effectiveness modelling to optimise active screening strategy for gambiense human African trypanosomiasis in endemic areas of the Democratic Republic of CongoTheoretical optimum strategy. Theoretical optimum strategy for the mean simulation of infection dynamics given a range of WTP values (horizontal axis). a–c examine the impact of different treatment coverage (pt) on a the optimal screening coverage, b the optimal screening interval and c the optimal number of zero-detections required to stop screening, to achieve the highest NMB for given WTP. These results assume a village population of 1000 where the disease in endemic. d–f examine the impact of different assumptions about population size and endemicity on d the optimal screening coverage, e the optimal screening interval and f the optimal number of active zero-detections required to stop screening. The demography and disease endemicity assumptions are as follows: a population of population 1,000 where the disease is endemic (‘1000 (E)’), a village of population 1000 where only one person is initially infected (single infection, or ‘1000 (S)’), a village of population 250 where disease is endemic (‘250 (E)’), and a village of population 1000 where disease is endemic and there exists a small probability of infectious importations (‘1000 (I)’). We fix zr=1 for all simulationsBack to article page