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Table 3 Comparison of serum DIDO1-, FOXJ2-, and CPSF2-Ab levels between HDs and patients with acute myocardial infarction (AMI) or diabetes mellitus (DM) examined by AlphaLISA

From: Serum anti-DIDO1, anti-CPSF2, and anti-FOXJ2 antibodies as predictive risk markers for acute ischemic stroke

Alpha analysis (antibody level)

DIDO1-Ab

FOXJ2-Ab

CPSF2-Ab

HD

Average

11,373

12,218

5571

SD

1939

6636

2390

Cutoff value

15,251

25,490

10,351

Positive no.

4

4

7

Positive (%)

3.1%

3.1%

5.5%

AMI

Average

11,634

22,965

5343

SD

2405

16,329

3070

Positive no.

10

44

6

Positive (%)

7.8%

34.4%

4.7%

P (AMI vs HD)

0.342

< 0.0001

0.508

DM

Average

11,199

21,718

7232

SD

2252

24,383

3798

Positive no.

7

29

17

Positive (%)

5.5%

22.7%

13.3%

P (DM vs HD)

0.508

< 0.0001

< 0.0001

  1. The antigens used were purified DIDO1-GST protein and synthetic peptides, bFOXJ2-426 and bCPSF2-607. The shown numbers are as described in Table 2; P values lower than 0.05 and positive rates higher than 10% are marked in bold. Box-whisker plots of the same results are shown in Fig. 3a, d, and g