Table 4 Changes in number of associations that are graded as having convincing evidence when one criterion is dropped or replaced by a more lenient version

Convincing

99

6.8%

 Replace P < 10⁻⁶ by <0.001

134

9.2%

 Replace P < 10⁻⁶ by < 0.05

142

9.7%

 Without the minimum number of cases criterion

149

10.2%

 Without the largest study at p < 0.05 criterion

103

7.1%

 Without the 95% prediction interval criterion

106

7.3%

 Without the heterogeneity I²<50% criterion

159

10.9%

 Without the small study effects criterion

122

8.4%

 Without the excess significance criterion

111

7.6%