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Table 2 Baseline variables associated with SARS-CoV-2 spike antibody levels 5–9 months after COVID-19 symptoms onset by multivariable stepwise regression models

From: Persistence and baseline determinants of seropositivity and reinfection rates in health care workers up to 12.5 months after COVID-19

 

Predictors

Spike

Receptor binding domain

Betaa

95%CI

P value

Beta

95%CI

P value

IgMb

Hospitalization

0.187

0.025

0.348

0.024

0.324

0.150

0.498

<0.001

Previous allergies

0.157

0.000

0.314

0.051

ns

ns

ns

ns

Sputum and/or hemoptysis

0.156

−0.050

0.363

0.137

0.268

0.047

0.489

0.018

Anosmia/hypogeusia

0.108

−0.003

0.220

0.057

0.091

−0.028

0.210

0.133

Fever

0.091

−0.038

0.219

0.165

0.112

−0.027

0.250

0.113

Digestive alterations

ns

ns

ns

ns

−0.089

−0.210

0.033

0.152

IgA

Fever

0.250

0.094

0.406

0.002

0.178

0.060

0.296

0.003

Previous allergies

ns

ns

ns

ns

0.157

0.016

0.298

0.029

Hospitalization

ns

ns

ns

ns

0.156

0.013

0.299

0.033

Shivers

0.160

0.024

0.296

0.022

0.087

−0.014

0.188

0.091

Anosmia/hypogeusia

0.139

0.004

0.273

0.043

ns

ns

ns

ns

Smoking

−0.269

−0.524

−0.015

0.038

−0.222

−0.411

−0.032

0.022

Nurses

−0.265

−0.443

−0.086

0.004

−0.223

−0.357

−0.090

0.001

Physicians

−0.186

−0.360

−0.003

0.046

−0.219

−0.352

−0.087

0.001

IgG

Anosmia/hypogeusia

0.413

0.258

0.568

<0.001

0.189

0.077

0.301

0.001

Fever

0.398

0.218

0.578

<0.001

0.301

0.169

0.432

<0.001

Previous allergies

0.269

0.053

0.485

0.015

0.137

−0.021

0.295

0.090

Hospitalization

0.187

−0.024

0.398

0.082

0.236

0.068

0.404

0.006

Age

0.007

0.000

0.014

0.050

0.006

0.001

0.011

0.023

Cough

0.124

−0.034

0.283

0.123

ns

ns

ns

ns

Digestive alterations

ns

ns

ns

ns

0.088

−0.025

0.202

0.126

Smoking

−0.295

−0.580

−0.009

0.043

ns

ns

ns

ns

Nurses

ns

ns

ns

ns

−0.187

−0.335

−0.039

0.014

Physicians

ns

ns

ns

ns

−0.105

−0.253

0.042

0.159

  1. aEstimate of the model (beta coefficient), see text for interpretation
  2. blog10MFI: logarithm 10 median fluorescent intensity (antibody levels)
  3. CI confidence interval of the model estimate (beta)
  4. ns not significant (not retained in the stepwise forward/backward multivariable model)