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Table 2 Baseline variables associated with SARS-CoV-2 spike antibody levels 5–9 months after COVID-19 symptoms onset by multivariable stepwise regression models

From: Persistence and baseline determinants of seropositivity and reinfection rates in health care workers up to 12.5 months after COVID-19

  Predictors Spike Receptor binding domain
Betaa 95%CI P value Beta 95%CI P value
IgMb Hospitalization 0.187 0.025 0.348 0.024 0.324 0.150 0.498 <0.001
Previous allergies 0.157 0.000 0.314 0.051 ns ns ns ns
Sputum and/or hemoptysis 0.156 −0.050 0.363 0.137 0.268 0.047 0.489 0.018
Anosmia/hypogeusia 0.108 −0.003 0.220 0.057 0.091 −0.028 0.210 0.133
Fever 0.091 −0.038 0.219 0.165 0.112 −0.027 0.250 0.113
Digestive alterations ns ns ns ns −0.089 −0.210 0.033 0.152
IgA Fever 0.250 0.094 0.406 0.002 0.178 0.060 0.296 0.003
Previous allergies ns ns ns ns 0.157 0.016 0.298 0.029
Hospitalization ns ns ns ns 0.156 0.013 0.299 0.033
Shivers 0.160 0.024 0.296 0.022 0.087 −0.014 0.188 0.091
Anosmia/hypogeusia 0.139 0.004 0.273 0.043 ns ns ns ns
Smoking −0.269 −0.524 −0.015 0.038 −0.222 −0.411 −0.032 0.022
Nurses −0.265 −0.443 −0.086 0.004 −0.223 −0.357 −0.090 0.001
Physicians −0.186 −0.360 −0.003 0.046 −0.219 −0.352 −0.087 0.001
IgG Anosmia/hypogeusia 0.413 0.258 0.568 <0.001 0.189 0.077 0.301 0.001
Fever 0.398 0.218 0.578 <0.001 0.301 0.169 0.432 <0.001
Previous allergies 0.269 0.053 0.485 0.015 0.137 −0.021 0.295 0.090
Hospitalization 0.187 −0.024 0.398 0.082 0.236 0.068 0.404 0.006
Age 0.007 0.000 0.014 0.050 0.006 0.001 0.011 0.023
Cough 0.124 −0.034 0.283 0.123 ns ns ns ns
Digestive alterations ns ns ns ns 0.088 −0.025 0.202 0.126
Smoking −0.295 −0.580 −0.009 0.043 ns ns ns ns
Nurses ns ns ns ns −0.187 −0.335 −0.039 0.014
Physicians ns ns ns ns −0.105 −0.253 0.042 0.159
  1. aEstimate of the model (beta coefficient), see text for interpretation
  2. blog10MFI: logarithm 10 median fluorescent intensity (antibody levels)
  3. CI confidence interval of the model estimate (beta)
  4. ns not significant (not retained in the stepwise forward/backward multivariable model)