Fig. 7

Difference between vaccinating all individuals (dashed lines) and vaccinating only antibody-negative individuals (solid lines). Three different vaccine profiles are considered (three columns). Plots show cumulative cases (rows 1 and 2), hospitalizations (rows 3 and 4), and deaths (rows 5 and 6) under both low supply (50,000 vaccines available) and ample supply (300,000 vaccines available). Green lines show the preferred 25/75 allocation in the 20–49 and 70+ age groups, and red lines show a 75/25 vaccine allocation. In Rhode Island, a vaccination campaign that is able to vaccinate only antibody-negative individuals will result in 0.5% to 1% fewer hospitalizations and deaths. Results for Massachusetts shown in Additional file 1: Figure S24