Fig. 1

The genome-wide associations of our Han Chinese samples. a The principal component analysis (PCA) of cases and controls genotyped with ASA SNP array. b The PCA result of the ASA subgroup 1 (2,055 cases and 1,823 controls). c The PCA results of the ASA subgroup 2 (607 cases and 1,186 controls). d The Manhattan plot of meta-analysis results of our Han Chinese samples (3,493 cases and 4,709 controls). e,f The locuszoom plots of the two newly identified risk loci (the lead SNPs were rs7192086 and rs57016637)