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Table 3 Estimated reporting rates of adverse events following immunization (AEFI) from nationwide surveillance by vaccine (per million dose)

From: Evaluation of the safety profile of COVID-19 vaccines: a rapid review

Vaccine Country Cut-off date Doses administrated AEFIs Crude rate Pooled rate (95% CI)
Pfizer/BioNTech       3424.5 (2725.7–4123.3)
  Austria May 28, 2021 3,495,168 7210 2062.8  
  Belgium June 8, 2021 3,216,657 8496 2641.3  
  Canada June 4, 2021 18,894,651 3763 199.2  
  Denmark June 8, 2021 2,094,751 15,537 7417.1  
  Estonia June 14, 2021 533,863 1333 2496.9  
  Finland June 9, 2021 2,587,708 1533 592.4  
  France June 3, 2021 29,685,000 23,947 806.7  
  Germany May 31, 2021 36,865,276 34,735 942.2  
  Iceland June 15, 2021 109,919 624 5676.9  
  Italy May 26, 2021 22,285,723 47,631 2137.3  
  Netherlands June 6, 2021 7,300,000 111,852 15,322.2  
  Norway June 8, 2021 2,414,340 3302 1367.7  
  Spain March 21, 2021 4,834,876 23,084 4774.5  
  Sweden June 10, 2021 4,568,479 15,789 3456.1  
  UK June 2, 2021 25,400,000 193,768 7628.7  
  USA February 16, 2021 28,374,410 48,196 1698.6  
  Portugal May 30, 2021 3,943,979 4782 1212.5  
  Slovakia June 10, 2021 1,961,407 2493 1271.0  
Moderna       8231.3 (7530.6–8931.9)
  Austria May 28, 2021 507,987 1645 3238.3  
  Belgium June 8, 2021 437,008 1787 4089.2  
  Canada June 4, 2021 5,096,282 2151 422.1  
  Denmark June 8, 2021 185,169 2510 13,555.2  
  Estonia June 14, 2021 75,581 159 2103.7  
  Finland June 9, 2021 298,480 82 274.7  
  France June 3, 2021 3,492,000 3540 1013.7  
  Germany May 31, 2021 3,972,764 8319 2094.0  
  Iceland June 15, 2021 18,502 296 15,998.3  
  Italy May 26, 2021 2,901,137 2564 883.8  
  Netherlands June 6, 2021 300,000 20,799 69,330.0  
  Norway June 8, 2021 318,193 497 1561.9  
  Portugal May 30, 2021 521,683 387 741.8  
  Slovakia June 10, 2021 296,050 559 1888.2  
  Spain March 21, 2021 304,715 2741 8995.3  
  Sweden June 10, 2021 597,293 4475 7492.1  
  UK June 2, 2021 460,000 9243 20,093.5  
  USA February 16, 2021 26,738,383 56,567 2115.6  
Janssen       2683.4 (2070.4–3296.4)
  Austria May 28, 2021 36,004 98 2721.9  
  Belgium June 8, 2021 94,285 167 1771.2  
  Denmark June 8, 2021 14,019 41 2924.6  
  Estonia June 14, 2021 16,475 82 4977.2  
  France June 3, 2021 336,038 80 238.1  
  Germany May 31, 2021 472,941 733 1549.9  
  Iceland June 15, 2021 35,726 125 3498.9  
  Italy May 26, 2021 503,155 171 339.9  
  Netherlands June 6, 2021 9,000 606 67,333.3  
  Portugal May 30, 2021 109,409 17 155.4  
  USA May 7, 2021 7,980,000 13,725 1719.9  
Oxford/AstraZeneca     13,996.5 (10,775.9–17,217.1)
  Argentina April 9, 2021 783,055 2069 2642.2  
  Austria May 28, 2021 941,745 17,132 18,191.8  
  Belgium June 8, 2021 1,348,696 7078 5248.0  
  Canada June 4, 2021 2,346,032 874 372.5  
  Denmark June 8, 2021 150,694 23.236 154.2  
  Estonia June 14, 2021 203,897 2486 12,192.4  
  Finland June 9, 2021 406,100 855 2105.4  
  France June 3, 2021 5,318,878 17,727 3332.8  
  Germany May 31, 2021 9,230,103 34,870 3777.9  
  Iceland June 15, 2021 60,044 604 10,059.3  
  Italy May 26, 2021 6,739,596 15,878 2355.9  
  Netherlands June 6, 2021 1,300,000 145,423 111,863.8  
  Norway June 8, 2021 261,624 6640 25,379.9  
  Portugal May 30, 2021 1,215,009 1509 1242.0  
  Slovakia June 10, 2021 641,528 2706 4218.1  
  Spain March 21, 2021 985,528 6343 6436.1  
  Sweden June 10, 2021 886,815 21,891 24,685.0  
  UK June 2, 2021 40,200,000 717,250 17,842.0  
Sinopharm     316.4 (285.8–347.0)
  Argentina April 9, 2021 1,295,940 410 316.4  
Sputnik V      7447.2 (7356.0–7538.4)
  Argentina April 9, 2021 3,414,158 25,426 7447.2