Table 1 Patient characteristics
No. (%) | Patients completed genomic profiling (n = 1166) | Patients with potentially actionable alterations (n = 781) | P value |
|---|---|---|---|
Median age (range) | 59 (18–92) | 57 (18–92) | 0.034 |
Sex | 0.010 | ||
 Male | 696 (60) | 420 (54) |  |
 Female | 470 (40) | 361 (46) |  |
ECOG PS | 0.613 | ||
 0 | 304 (26) | 207 (27) |  |
 1 | 799 (69) | 524 (67) |  |
 2 | 63 (5) | 50 (6) |  |
Histology | < 0.001 | ||
 LUAD | 901 (77) | 681 (87) |  |
 LUSC | 108 (9) | 46 (6) |  |
 Othersa | 157 (13) | 54 (7) |  |
Smoking status | 0.002 | ||
 Never | 684 (59) | 495 (63) |  |
 Former/current | 391 (34) | 207 (27) |  |
 Unknown | 91 (8) | 79 (10) |  |
Disease stage | < 0.001 | ||
 III | 107 (9) | 32 (4) |  |
 IV | 1059 (91) | 749 (96) |  |
Number of prior therapies | < 0.001 | ||
 Median (range) | 0 (0–12) | 1 (0–8) |  |
 0 | 657 (56) | 230 (29) |  |
 1 | 204 (17) | 274 (35) |  |
 ≥2 | 305 (26) | 277 (36) |  |