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Table 1 Background characteristics of study participants (N=796)

From: Elevated risk of attention deficit hyperactivity disorder (ADHD) in Japanese children with higher genetic susceptibility to ADHD with a birth weight under 2000 g

Characteristics

n

%

Mean or median

SD or IQR

Children’s characteristics

    

 Birth order, n (%)

    

  First

401

50.4

  

  Second or higher

395

49.6

  

 Gender, n (%)

    

  Girls

392

49.2

  

  Boys

404

50.8

  

 Gestational age at birth in week, mean (SD)

  

38.9

1.52

 Preterm birth, n (%)

    

  Yes

51

6.4

  

  No

745

93.6

  

 Birth weight (g), mean (SD)

  

2949.3

440.1

  <2000 g

19

2.4

  

  2000–2499 g

82

10.3

  

  ≥2500 g

695

87.3

  

 ADHD-PRS, mean (SD)

  

0.0022

1.01

 ADHD-RS total score, median (IQR)

  

5a

1–10b

  Inattention, median (IQR)

  

3a

1–7b

  Hyperactivity, median (IQR)

  

1a

0-3b

Parent’s characteristics

    

 Mother’s age at delivery, n (%)

    

  <35 years

567

71.2

  

  ≥35 years

229

28.8

  

 Maternal educational attainment, n (%)

    

  ≤12 years

246

30.9

  

  >12 years

550

69.1

  

 Maternal pre-pregnancy BMI, n (%)

    

  Underweight (<18.5)

170

21.3

  

  Normal weight (18.5-24.9)

541

68.0

  

  Overweight (≥25.0)

85

10.7

  

 Pre-pregnancy or during pregnancy smoking history, n (%)

    

  Yes

155

19.5

  

  No

641

80.5

  

 Alcohol consumption during pregnancy, n (%)

    

  Yes

110

13.8

  

  No

686

86.2

  

 Father’s age at birth

    

  <25 years

45

5.6

  

  25–34 years

456

57.3

  

  ≥35 years

295

37.1

  

 Father’s education at birth

    

  ≤12 years

59

7.4

  

  >12 years

737

92.6

  

 Household annual income at birth in JPY

    

  ≤3 million

36

4.5

  

  3–8 million

604

75.9

  

  ≥8 million

156

19.6

  
  1. Note: aValues present median; bvalues present interquartile range; ADHD-RS, attention deficit/hyperactivity disorder rating scale; BMI, body mass index; IQR, interquartile range; PRS, polygenic risk score; SD, standard deviation; JPY, Japanese yen