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Table 4 The associations between dementia and the frailty index (FI) constructed from traditional risk factors for dementia (FI-TRF, model 1) and non-traditional risk factors for dementia (FI-NTRF, model 2) assessed by Cox regression in the full sample adjusted for age, sex, education, and tobacco use. Hazard ratios (HRs) and 95% confidence intervals are presented for a 10% increase in the FI-TRF and FI-NTRF

From: Frailty and the risk of dementia: is the association explained by shared environmental and genetic factors?

  Full sample
Model 1
HR (95% CI)
Model 2
HR (95% CI)
FI-TRF 1.13 (1.10, 1.17)*  
FI-NTRF   1.13 (1.09, 1.18)*
Male sex 0.90 (0.83, 0.98)* 0.87 (0.80, 0.94)*
Age at FI measurement 1.15 (1.14, 1.16)* 1.15 (1.14, 1.16)*
Years of education 0.97 (0.96, 0.98)* 0.97 (0.96, 0.98)*
Tobacco user 1.21 (1.11, 1.30)* 1.19 (1.10, 1.29)*
  1. *P < 0.05