Computer-assisted quantification of tumor-associated collagen signatures to improve the prognosis prediction of breast cancer

Table 3 The performance comparison of different models for predicting 5-year disease-free survival

Model	Training cohort				Internal validation cohort				External validation cohort
Model	*AUC*	*ACC*	*SEN*	*SPE*	*AUC*	*ACC*	*SEN*	*SPE*	*AUC*	*ACC*	*SEN*	*SPE*
CLI	74.9	71.5	64.7	75.7	73.3	69.5	58.0	75.2	72.4	69.6	51.1	79.8
TCMF-score	78.1	74.6	66.9	79.3	77.2	71.9	65.2	75.2	80.6	73.1	60.0	80.4
TACS-score	84.5	81.4	78.2	83.3	81.8	74.6	69.6	77.0	81.8	75.9	73.3	77.3
TCMF+TACS	87.6	82.0	84.2	80.6	86.2	78.1	80.4	77.0	84.8	76.3	78.9	74.9
CLI+TCMF+TACS	90.5	85.6	79.0	89.6	89.6	82.6	75.0	86.5	88.2	82.2	70.0	89.0

Note: AUC, area under the receiver operating characteristic curve; ACC, accuracy; SEN, sensitivity; SPE, specificity

ISSN: 1741-7015