Fig. 1
From: IRF7 and RNH1 are modifying factors of HIV-1 reservoirs: a genome-wide association analysis
Study design and host characteristics. A Overview of the study design. B Patient characteristics corresponding to Table 1, including distributions of HIV nucleic acid measurement (CA HIV-1 DNA, CA HIV-1 RNA, and RNA:DNA ratio) and host factors (age, CD4 nadir, and duration of HIV-1 infection). C Spearman’s ρ among CA HIV-1 DNA, CA HIV-1 RNA, RNA:DNA ratio, and other host factors. The top left triangle shows the ρ value, in which the negative and positive correlation values are colored in blue and red, respectively. The bottom right triangle shows the FDR of each correlation analysis. D Correlation between CA HIV-1 RNA and CA HIV-1 DNA. Theoretically, CA HIV-1 RNA is highly correlated to CA HIV-1 DNA, while, in our data, we found they are correlated by a Pearson’s r = 0.69 (P < 2.0 × 10−16)