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Table 2 COVID-19-related disruptions to measles burden and vaccination impact. Total burden (cases, deaths, and DALYs) and vaccine impact (cases, deaths, and DALYs averted) in ten high measles burden countries over 2000–2050 are presented, based on coverage estimates without and with disruptions caused by COVID-19. Proportionate changes due to COVID-19 disruptions are shown in parentheses. Model scenarios in this analysis were conducted under the ‘full-update’ model, with the assumption of R0 = 16 and implementation of MCV1, MCV2, and SIA. Abbreviations: DALY disability-adjusted life years, MCV1 first routine dose of measles-containing vaccine, MCV2 second routine dose of measles-containing vaccine, SIA supplementary immunisation activity

From: Effect of evidence updates on key determinants of measles vaccination impact: a DynaMICE modelling study in ten high-burden countries

 

Measles burden over 2000–2050

Vaccine impact over 2000–2050

Measurements (millions)

Non-COVID-19 scenario

COVID-19 scenario

Additional burden due to COVID-19

Non-COVID-19 scenario

COVID-19 scenario

Cases

253.43

(ref)

260.56

(+ 2.81%)

7.12

2243.81

(ref)

2236.69

(− 0.32%)

Deaths

3.76

(ref)

3.86

(+ 2.90%)

0.109

42.64

(ref)

42.53

(− 0.26%)

DALYs

233.43

(ref)

240.13

(+ 2.87%)

6.70

2797.73

(ref)

2791.03

(− 0.24%)