Table 3 Mean differences in rate of cognitive change (SD/year) in women
From: Different hypertension thresholds and cognitive decline: a pooled analysis of three ageing cohorts
BP Group | HRS (n = 4154) | ELSA (n = 2996) | CHARLS (n = 2759) | Pooled analysis (n = 9909) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
β (95% Cl)* | P value | β (95% Cl)* | P value | β (95% Cl)* | P value | Pooled β (95% Cl)* | P value | I2 (%) | P value | |
Global | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 Normal | −0.002 (−0.013 to 0.009) | 0.747 | 0.017 (0.003 to 0.030) | 0.015 | 0.006 (−0.010 to 0.022) | 0.471 | 0.006 (−0.005 to 0.018) | 0.269 | 54.8 | 0.109 |
 Borderline | Reference | / | Reference | / | Reference | / | Reference | / | / | / |
 High | −0.020 (− 0.028 to − 0.012) | < 0.001 | −0.022 (− 0.033 to − 0.012) | < 0.001 | − 0.004 (− 0.019 to 0.011) | 0.612 | −0.017 (− 0.026 to − 0.008) | < 0.001 | 53.6 | 0.116 |
Memory | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 Normal | −0.004 (− 0.012 to 0.004) | 0.358 | 0.012 (0.003 to 0.022) | 0.011 | 0.016 (−0.005 to 0.037) | 0.126 | 0.007 (−0.006 to 0.020) | 0.317 | 74.9 | 0.019 |
 Borderline | Reference | / | Reference | / | Reference | / | Reference | / | / | / |
 High | −0.013 (− 0.019 to − 0.006) | < 0.001 | − 0.015 (− 0.022 to − 0.008) | < 0.001 | − 0.008 (− 0.027 to 0.011) | 0.409 | −0.013 (− 0.018 to − 0.009) | < 0.001 | 0.0 | 0.726 |
Executive function | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 Normal | 0.000 (−0.008 to 0.007) | 0.956 | 0.010 (0.001 to 0.019) | 0.031 | 0.001 (− 0.014 to 0.016) | 0.866 | 0.004 (− 0.003 to 0.011) | 0.285 | 33.2 | 0.224 |
 Borderline | Reference | / | Reference | / | Reference | / | Reference | / | / | / |
 High | −0.005 (−0.011 to 0.001) | 0.089 | −0.009 (− 0.015 to − 0.002) | 0.016 | 0.005 (−0.009 to 0.019) | 0.494 | −0.005 (− 0.011 to 0.000) | 0.069 | 31.1 | 0.234 |
Orientation | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 Normal | 0.003 (− 0.011 to 0.016) | 0.709 | 0.011 (−0.005 to 0.026) | 0.193 | −0.004 (− 0.022 to 0.014) | 0.671 | 0.004 (−0.005 to 0.013) | 0.439 | 0.0 | 0.493 |
 Borderline | Reference | / | Reference | / | Reference | / | Reference | / | / | / |
 High | −0.016 (− 0.026 to − 0.005) | 0.004 | −0.022 (− 0.034 to − 0.010) | < 0.001 | − 0.006 (− 0.022 to 0.011) | 0.513 | −0.016 (− 0.024 to − 0.008) | < 0.001 | 20.6 | 0.284 |