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Table 2 Dietary intakes of participants according to ELISA-S test status, NutriNet-Santé cohort study (2009–2020)—SAPRIS-SERO project

From: Nutritional risk factors for SARS-CoV-2 infection: a prospective study within the NutriNet-Santé cohort

 

ELISA-S negative

(n=7455)

ELISA-S positive

(n=311)

 

Mean ± SD

Mean ± SD

P*

Macronutrients

 Energy, without alcohol (kcal/day)

1800 ± 400

1800 ± 400

0.51

 Alcohol (g/day)

8.5 ± 10

7.6 ± 10

0.35

 Protein (g/day)

75 ± 20

74 ± 20

0.46

 Carbohydrates, total (g/day)

190 ± 50

200 ± 50

0.34

 Sugars (g/day)

89 ± 30

90 ± 30

0.78

 Fiber (g/day)

22 ± 7

21 ± 6

0.02

 Fiber, soluble (g/day)

8 ± 3

7.5 ± 2

0.004

 Fiber, insoluble (g/day)

14 ± 5

13 ± 4

0.046

 Fatty acids, total (g/day)

84 ± 20

85 ± 20

0.54

 Saturated fatty acids (g/day)

35 ± 10

36 ± 10

0.14

 Monounsaturated fatty acids (g/day)

31 ± 9

31 ± 8

0.80

 Polyunsaturated fatty acids (g/day)

12 ± 4

12 ± 4

0.37

 n-3 polyunsaturated fatty acids, total (g/day)

1.5 ± 0.9

1.4 ± 0.8

0.0004

 n-3 linolenic acid (g/day)

1.1 ± 0.8

1.0 ± 0.7

0.006

 n-3 eicosapentaenoic acid (g/day)

0.14 ± 0.1

0.11 ± 0.1

0.002

 n-3 docosahexaenoic acid (g/day)

0.19 ± 0.1

0.15 ± 0.1

0.0003

 n-6 polyunsaturated fatty acids, total (g/day)

10 ± 4

9.9 ± 4

0.65

 Cholesterol (mg/day)

320 ± 100

308 ± 100

0.19

Vitamins

 Vitamin A† (μg/day)

1200 ± 600

1100 ± 500

0.03

 Vitamin B1 (mg/day)

1.1 ± 0.4

1.2 ± 0.4

0.24

 Vitamin B2 (mg/day)

1.7 ± 0.5

1.7 ± 0.4

0.59

 Vitamin B3/PP (mg/day)

18 ± 6

18 ± 6

0.94

 Vitamin B5 (mg/day)

5.2 ± 1

5.1 ± 1

0.62

 Vitamin B6 (mg/day)

1.7 ± 0.5

1.7 ± 0.4

0.13

 Vitamin B9 (μg/day)

330 ± 90

320 ± 90

0.004

 Vitamin B12 (μg/day)

5.1 ± 4

4.5 ± 3

0.01

 Vitamin C (mg/day)

110 ± 50

102 ± 40

0.002

 Vitamin D (μg/day)

2.7 ± 2

2.5 ± 2

0.04

 Vitamin E (mg/day)

12.0 ± 4

12 ± 4

0.41

 Vitamin K (μg/day)

160 ± 100

140 ± 90

0.0001

  Vitamin K from plant origin (μg/day)

130 ± 100

110 ± 80

0.0001

  Vitamin K from animal origin (μg/day)

26 ± 20

25 ± 20

0.99

Minerals

 Selenium (μg/day)

69 ± 20

69 ± 21

0.64

 Zinc (mg/day)

11 ± 3

11 ± 3

0.96

 Calcium (mg/day)

940 ± 300

960 ± 300

0.15

 Magnesium (mg/day)

380 ± 100

370 ± 100

0.39

 Phosphorus (mg/day)

1300 ± 400

1300 ± 300

0.39

 Potassium (mg/day)

3060 ± 800

2900 ± 700

0.01

 Sodium (mg/day)

3060 ± 900

3007 ± 800

0.40

 Copper (mg/day)

1.9 ± 0.9

1.8 ± 0.8

0.42

 Iron (mg/day)

14 ± 5

14 ± 4

0.18

 Iodine (μg/day)

190 ± 100

190 ± 100

0.48

 Manganese (mg/day)

4.7 ± 2

4.6 ± 2

0.40

Food groups

 Fruit and vegetables (g/day)

460 ± 200

410 ± 200

0.0001

 Legumes (g/day)

18 ± 20

17 ± 20

0.99

 Nuts, unsalted (g/day)

6.9 ± 10

6.5 ± 10

0.10

 Starchy foods‡ (g/day)

180 ± 90

180 ± 80

0.14

 Red meat (g/day)

32 ± 30

29 ± 20

0.09

 Processed meat (g/day)

27 ± 20

28 ± 30

0.87

 Poultry (g/day)

20 ± 19

21 ± 20

0.28

 Eggs (g/day)

17 ± 20

15 ± 10

0.01

 Fish (g/day)

28 ± 20

24 ± 20

0.002

 Seafood (g/day)

7.5 ± 10

6.5 ± 10

0.07

 Dairy products (g/day)

180 ± 100

190 ± 100

0.03

 Cakes, cookies and pastries (g/day)

48 ± 40

54 ± 40

0.02

 Sweet products§ (g/day)

72 ± 50

75 ± 50

0.09

 Breakfast cereals (g/day)

5.5 ± 10

7.2 ± 20

0.02

 Unsweetened drinks (g/day)

1200 ± 500

1300 ± 500

0.07

 Sugary drinks (g/day)

59 ± 80

64 ± 90

0.14

 Alcoholic drinks (g/day)

101 ± 100

94 ± 100

0.43

 Added fat, plant origin (e.g., oil) (g/day)

14 ± 8

13 ± 7

0.04

 Added fat, animal origin (e.g., butter) (g/day)

9.6 ± 7

9.7 ± 8

0.72

Overall diet quality

 sPNNS-GS2||

2.5 ± 3

2.4 ± 3.1

0.47

 AHEI-2010¶

54 ± 10

52.4 ± 11.8

0.005

 Ultra-processed foods** (%)

15 ± 7

15.0 ± 6.7

0.23

  1. *P values from Wilcoxon Mann-Whitney tests for unadjusted associations between individual characteristics and ELISA-S test status
  2. †Total vitamin A including retinol and beta-carotene, calculated as retinol equivalent (1 mg retinol = 6 mg beta-carotene)
  3. ‡Bread, pasta, rice, potatoes, starchy vegetables, etc.
  4. §Chocolate, sweets, honey, sugary desserts, etc.
  5. || Programme National Nutrition Santé-guidelines score 2 (simplified, sPNNS-GS2) summarizing the 2017 French dietary guidelines, ranging from ranging from − 17 to 14.25 [31]
  6. ¶Alternative Healthy Eating Index (AHEI)-2010 score, ranging from 0 to 100 [30]
  7. **Proportion of ultra-processed foods in the diet, based on the NOVA classification [33]